Trial reportTrials2014
Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial.
Trial report in Trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01844596 (Optimizing Linkage and Retention to Hypertension Care in Rural Kenya), which is not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing Linkage and Retention to Hypertension Care in Rural Kenya
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care.The Cochrane database of systematic reviews · 2025Pooled it
- Interventions and contextual factors to improve retention in care for patients with hypertension in primary care: Hermeneutic systematic review.Preventive medicine · 2024Pooled it
- Non-pharmacological interventions to achieve blood pressure control in African patients: a systematic review.BMJ open · 2022Pooled it
- Pharmacotherapy for hypertension in Sub-Saharan Africa: a systematic review and network meta-analysis.BMC medicine · 2020Pooled it
- Mobile health for non-communicable diseases in Sub-Saharan Africa: a systematic review of the literature and strategic framework for research.Globalization and health · 2014Pooled it
- Impact of home-based follow-up care on hypertension control among patients attending Thika Level Five Hospital, Kiambu County, Kenya: A randomized control study.International health · 2025Trial
- Community Health Workers Improve Linkage to Hypertension Care in Western Kenya.Journal of the American College of Cardiology · 2019Trial
- Trial
- Driving NCD screening at scale: outcomes of a digital, CHW-led hypertension surveillance program in rural Rwanda.BMC public health · 2026Article
- Barriers to and facilitators of linkage to care following hypertension and diabetes screening among health workers in Zimbabwe: A mixed method study.PLOS global public health · 2025Article
- Community-Based Participatory Research and System Dynamics Modeling for Improving Retention in Hypertension Care.JAMA network open · 2024Article
- Characteristics and Patterns of Retention in Hypertension Care in Primary Care Settings From the Hypertension Treatment in Nigeria Program.JAMA network open · 2022Article
- Effect of Nurse-Based Management of Hypertension in Rural Western Kenya.Global heart · 2020Article
- Article
- Hypertension management in rural western Kenya: a needs-based health workforce estimation model.Human resources for health · 2019Article
- The burden of hypertension in the emergency department and linkage to care: A prospective cohort study in Tanzania.PloS one · 2019Article
- Task-shifting for cardiovascular risk factor management: lessons from the Global Alliance for Chronic Diseases.BMJ global health · 2018Article
- Ensuring Patient-Centered Access to Cardiovascular Disease Medicines in Low-Income and Middle-Income Countries Through Health-System Strengthening.Cardiology clinics · 2017Review
- Innovative Approaches to Hypertension Control in Low- and Middle-Income Countries.Cardiology clinics · 2017Review
- Diabetes in sub-Saharan Africa - from policy to practice to progress: targeting the existing gaps for future care for diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundHypertension is the leading global risk factor for mortality. Hypertension treatment and control rates are low worldwide, and delays in seeking care are associated with increased mortality. Thus, a critical component of hypertension management is to optimize linkage and retention to care. METHODS/
designThis study investigates whether community health workers, equipped with a tailored behavioral communication strategy and smartphone technology, can increase linkage and retention of hypertensive individuals to a hypertension care program and significantly reduce blood pressure among them. The study will be conducted in the Kosirai and Turbo Divisions of western Kenya. An initial phase of qualitative inquiry will assess facilitators and barriers of linkage and retention to care using a modified Health Belief Model as a conceptual framework. Subsequently, we will conduct a cluster randomized controlled trial with three arms: 1) usual care (community health workers with the standard level of hypertension care training); 2) community health workers with an additional tailored behavioral communication strategy; and 3) community health workers with a tailored behavioral communication strategy who are also equipped with smartphone technology. The co-primary outcome measures are: 1) linkage to hypertension care, and 2) one-year change in systolic blood pressure among hypertensive individuals. Cost-effectiveness analysis will be conducted in terms of costs per unit decrease in blood pressure and costs per disability-adjusted life year gained. DISCUSSION: This study will provide evidence regarding the effectiveness and cost-effectiveness of strategies to optimize linkage and retention to hypertension care that can be applicable to non-communicable disease management in low- and middle-income countries.
trial registrationThis trial is registered with (NCT01844596) on 30 April 2013.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.