Evidence map›Paper›PMID 24766930›Full record

ArticleBMC medical ethics2014

Knowledge and attitudes to personal genomics testing for complex diseases among Nigerians.

Lawrence Fagbemiro, Clement Adebamowo

Abstract read
In one paragraph

Article in BMC medical ethics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study.International journal of stroke : official journal of the International Stroke Society · 2019
    Article
  8. Article
  9. Article
  10. Article
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  12. Article
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  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lawrence FagbemiroNational Drug and Poison Information Centre, Federal Ministry of Health, Abuja, FCT, Nigeria. fagbemiro2001@yahoo.co.uk.
Clement Adebamowo

Funding

West African Bioethics Training ProgramR25TW007091 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI ADEBAMOWO, CLEMENT ADEBAYO · 2004 to 2015
$2.5M
FIC NIH HHS 3R25TW007091-06S2FIC NIH HHS D43 TW007091
6 · The paper itself

Abstract

backgroundThe study examined the knowledge and attitudes to personal genomics testing for complex diseases among Nigerians and identified how the knowledge and attitudes vary with gender, age, religion, education and related factors.

methodsData were collected using qualitative method in 2 districts of the Federal Capital Territory. In the study, eight (8) Focused Group Discussions (FGDs) and twenty seven (27) Key Informant Interviews (KIIs) were conducted. Participants for the research were recruited among healthy Nigerians, individuals with complex diseases, health care professionals, community leaders and health policy makers.

resultAnalysis of the result showed that most respondents in both FGDs and KIIs had limited knowledge about genomics test initially. Their understanding of the test however improved after explanation on its concept. Participants showed positive attitude towards genomics tests. Nevertheless they expressed fear over direct to consumer personal genomics testing, testing unborn babies and disclosure of results to third parties. Culture and religion were found to influence the perspectives of respondents on genomics test particularly those aspects that could either directly contradict their beliefs and practices or lead to actions which contradict them.

conclusionIn conclusion, most Nigerians interviewed had limited knowledge of genomics test but with supportive attitude towards its use in predicting future risk of complex diseases after understanding the test concept. Genomics testing for complex diseases was not a common practice in Nigeria.

Indexed as

Genetic Predisposition to DiseaseGenetic TestingAdultBlack PeopleComprehensionCross-Sectional StudiesFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHumansInfantMaleMiddle AgedNigeriaPatient Acceptance of Health CareQualitative Research

Identifiers

PMID24766930
PMCPMC4005395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.