ArticleBMC plant biology2014
Homologous haplotypes, expression, genetic effects and geographic distribution of the wheat yield gene TaGW2.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed.
- Antagonistic effects of selection on alleles associated with seed size and seed dormancy in wheat.Genome biology · 2025Article
- Genomic-wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.).The plant genome · 2024Article
- Knockout of GRAIN WIDTH2 has a dual effect on enhancing leaf rust resistance and increasing grain weight in wheat.Plant biotechnology journal · 2024Article
- Fine mapping of a major QTL, qKl-1BL controlling kernel length in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- A novel variation ofMolecular breeding : new strategies in plant improvement · 2024Article
- Independent genetic factors control floret number and spikelet number inFrontiers in plant science · 2024Article
- A high-resolution genotype-phenotype map identifies the TaSPL17 controlling grain number and size in wheat.Genome biology · 2023Article
- Genomics for Yield and Yield Components in Durum Wheat.Plants (Basel, Switzerland) · 2023Review
- Article
- Breeding effects on durum wheat traits detected using GWAS and haplotype block analysis.Frontiers in plant science · 2023Article
- Responses of wheat kernel weight to diverse allelic combinations under projected climate change conditions.Frontiers in plant science · 2023Article
- Genome-Wide Association Study in Bread Wheat Identifies Genomic Regions Associated with Grain Yield and Quality under Contrasting Water Availability.International journal of molecular sciences · 2022Article
- A superior allele of the wheat gene TaGL3.3-5B, selected in the breeding process, contributes to seed size and weight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Characterization of TaSPP-5A gene associated with sucrose content in wheat (Triticum aestivum L.).BMC plant biology · 2022Article
- Exploiting Wild Emmer Wheat Diversity to Improve Wheat A and B Genomes in Breeding for Heat Stress Adaptation.Frontiers in plant science · 2022Article
- CRISPR-Cas9 mediated mutation in GRAIN WIDTH and WEIGHT2 (GW2) locus improves aleurone layer and grain nutritional quality in rice.Scientific reports · 2021Article
- Identification and fine mapping of alien fragments associated with enhanced grain weight from Agropyron cristatum chromosome 7P in common wheat backgrounds.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Direct introgression of untapped diversity into elite wheat lines.Nature food · 2021Article
- Combining Protein Content and Grain Yield by Genetic Dissection in Bread Wheat under Low-Input Management.Foods (Basel, Switzerland) · 2021Article
- Genomics-assisted breeding for successful development of multiple-stress-tolerant, climate-smart rice for southern and southeastern Asia.The plant genome · 2021Article
3 more citing papers are in PubMed but not listed here.
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8 authors.
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Abstract
backgroundTaGW2-6A, cloned in earlier research, strongly influences wheat grain width and TKW. Here, we mainly analyzed haplotypes of TaGW2-6B and their effects on TKW and interaction with haplotypes at TaGW2-6A.
resultsAbout 2.9 kb of the promoter sequences of TaGW2-6B and TaGW2-6D were cloned in 34 bread wheat cultivars. Eleven SNPs were detected in the promoter region of TaGW2-6B, forming 4 haplotypes, but no divergence was detected in the TaGW2-6D promoter or coding region. Three molecular markers including CAPS, dCAPS and ACAS, were developed to distinguish the TaGW2-6B haplotypes. Haplotype association analysis indicated that TaGW2-6B has a stronger influence than TaGW2-6A on TKW, and Hap-6B-1 was a favored haplotype increasing grain width and weight that had undergone strong positive selection in global wheat breeding. However, clear geographic distribution differences for TaGW2-6A haplotypes were found; Hap-6A-A was favored in Chinese, Australian and Russian cultivars, whereas Hap-6A-G was preferred in European, American and CIMMYT cultivars. This difference might be caused by a flowering and maturity time difference between the two haplotypes. Hap-6A-A is the earlier type. Haplotype interaction analysis between TaGW2-6A and TaGW2-6B showed additive effects between the favored haplotypes. Hap-6A-A/Hap-6B-1 was the best combination to increase TKW. Relative expression analysis of the three TaGW2 homoeologous genes in 22 cultivars revealed that TaGW2-6A underwent the highest expression. TaGW2-6D was the least expressed during grain development and TaGW2-6B was intermediate. Diversity of the three genes was negatively correlated with their effect on TKW.
conclusionsGenetic effects, expression patterns and historic changes of haplotypes at three homoeologous genes of TaGW2 influencing yield were dissected in wheat cultivars. Strong and constant selection to favored haplotypes has been found in global wheat breeding during the past century. This research also provides a valuable case for understanding interaction of genes that control complex traits in polyploid species.
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