Evidence map›Paper›PMID 24766570›Full record

Observational studyJournal of clinical hypertension (Greenwich, Conn.)2014

Renal sympathetic denervation: early impact on ambulatory resistant hypertension.

Marius Schwerg, Christian Heupel, Dino Strajnic, Gert Baumann, Michael Laule, Verena Stangl, Karl Stangl

Abstract readObservational Study
In one paragraph

Observational study in Journal of clinical hypertension (Greenwich, Conn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Renal nerve ablation for resistant hypertension: the dust has not yet settled.Journal of clinical hypertension (Greenwich, Conn.) · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Marius SchwergDepartment of Cardiology and Angiology, Campus Mitte Charité - Universitätsmedizin, Berlin, Germany.
Christian Heupel
Dino Strajnic
Gert Baumann
Michael Laule
Verena Stangl
Karl Stangl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although guidelines recommend ambulatory blood pressure (BP) monitoring (ABPM), few data are available regarding the effects of renal denervation (RDN) on 24-hour ABPM values. A total of 44 patients with mean systolic BP ≥135 mm Hg on ABPM despite adequate therapy were included. Basal systolic BP (SBP) and diastolic BP (DBP) were 154±11 mm Hg and 86±12 mm Hg, respectively. At 1 month, SBP and DBP were reduced to 146±18 mm Hg (P=.01) and 82±14 mm Hg and showed no further decrease up to 6 months. Only 55% of the patients responded to RDN (≥-5 mm Hg SBP), with a mean responder rate drop of 21/11 mm Hg. Neither the number of ablation points nor the amount of impedance drop was predictive of response. Only approximately half of patients with resistant hypertension responded to RDN. However, in these responders, a remarkable reduction of 24-hour BP occurred as early as 1 month after RDN.

Indexed as

Blood Pressure Monitoring, AmbulatoryBlood PressureFemaleFollow-Up StudiesHumansHypertensionKidneyMaleMiddle AgedProspective StudiesSympathectomySympathetic Nervous SystemTreatment Outcome

Identifiers

PMID24766570
PMCPMC8031809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.