Evidence map›Paper›PMID 24766561›Full record

ArticleBrain connectivity2014

Frequent and discriminative subnetwork mining for mild cognitive impairment classification.

Fei Fei, Biao Jie, Daoqiang Zhang

Open access · greenAbstract read
In one paragraph

Article in Brain connectivity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fei FeiCollege of Computer Science and Technology, Nanjing University of Aeronautics and Astronautics , Nanjing, China .
Biao Jie
Daoqiang Zhang
Nanjing University of Aeronautics and Astronautics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies on brain networks have suggested that many brain diseases, such as Alzheimer's disease and mild cognitive impairment (MCI), are related to a large-scale brain network, rather than individual brain regions. However, it is challenging to find such a network from the whole brain network due to the complexity of brain networks. In this article, the authors propose a novel method to mine the discriminative subnetworks for classifying MCI patients from healthy controls (HC). Specifically, the authors first extract a set of frequent subnetworks from each of the two groups (i.e., MCI and HC), respectively. Then, measure the discriminative ability of those frequent subnetworks using the graph kernel-based classification method and select the most discriminative subnetworks for subsequent classification. The results on the functional connectivity networks of 12 MCI and 25 HC show that this method can obtain competitive results compared with state-of-the-art methods on MCI classification.

Indexed as

AlgorithmsAgedAged, 80 and overBrainBrain MappingCase-Control StudiesCognitive DysfunctionFemaleHumansMagnetic Resonance ImagingMaleNerve NetNeural PathwaysReproducibility of Resultsfunctional connectivity networkgraph kernelmild cognitive impairmentsubgraph mining

Identifiers

PMID24766561
PMCPMC4064736
OpenAlexW1976755607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.