ArticleJournal of clinical hypertension (Greenwich, Conn.)2014
Aortic to brachial pulse pressure amplification as functional marker and predictor of renal function loss in chronic kidney disease.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Association Between Central-Peripheral Blood Pressure Amplification and Structural and Functional Cardiac Properties in Children, Adolescents, and Adults: Impact of the Amplification Parameter, Recording System and Calibration Scheme.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Determinants of pulse pressure amplification in hypertensive and diabetic patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Elevated pulse amplification in hypertensive patients with advanced kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Ambulatory arterial stiffness in chronic kidney disease: a methodological review.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Review
- Renal glomerular dysfunction in relation to retinal arteriolar narrowing and high pulse pressure in seniors.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
- Arterial function and cardiorenal damage.Journal of clinical hypertension (Greenwich, Conn.) · 2014Article
- Aortic to brachial pulse pressure amplification as functional marker and predictor of renal function loss in chronic kidney disease.Journal of clinical hypertension (Greenwich, Conn.) · 2014Article
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Abstract
Pulse pressure amplification (PPA) reflects large artery function. Its contribution in chronic kidney disease (CKD) remains uncertain. The authors assessed PPA in CKD progression in patients with CKD stage 2 to 4 (n=128) and 89 controls (follow-up: 42 months). PPA was reduced in CKD patients as compared with control patients and associated with decline in renal function. Sixteen renal endpoints, defined by 50% loss of renal function or start of renal replacement therapy, were detected. In Cox regression analysis, PPA, estimated glomerular filtration rate, and proteinuria predicted renal endpoints. Patients with CKD stage 4 and low PPA had the highest risk for developing renal endpoints (unadjusted 8.1; 2.4-27.7 and adjusted for age and proteinuria 5.6; 1.5-21.9, log-rank P<.001). Taken together, PPA is reduced in CKD and is associated with declining renal function. In addition, low PPA predicts renal endpoints in severe CKD. Furthermore, this study emphasizes the role of systolic blood pressure as a major determinant of PPA.
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