ReviewInfection ecology & epidemiology2014
ESBL-producing Enterobacteriaceae in Africa - a non-systematic literature review of research published 2008-2012.
Review in Infection ecology & epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Extended-spectrum beta-lactamases in poultry in Africa: a systematic review.Frontiers in antibiotics · 2023Pooled it
- High prevalence of antibiotic resistance in commensal Escherichia coli from healthy human sources in community settings.Scientific reports · 2021Pooled it
- Prevalence of multidrug-, extensive drug-, and pandrug-resistant commensalGlobal health action · 2019Pooled it
- Gut mucosal colonisation with extended-spectrum beta-lactamase producing Enterobacteriaceae in sub-Saharan Africa: a systematic review and meta-analysis.Wellcome open research · 2019Pooled it
- Antimicrobial resistance among children in sub-Saharan Africa.The Lancet. Infectious diseases · 2018Pooled it
- Extended spectrum beta lactamases and carbapenemase-producingOne health (Amsterdam, Netherlands) · 2026Review
- Alarming resistance to third-generation cephalosporins and carbapenems amongAfrican journal of laboratory medicine · 2026Article
- Gut colonization, acquisition, and persistence of β-lactamase-producing Enterobacterales among hospitalized patients in Addis Ababa, Ethiopia.BMC infectious diseases · 2025Article
- Clinical outcomes and risk factors associated with bloodstream infections caused by multidrug-resistant Gram-negative bacteria in hospitalized patients: a prospective cohort study in Libya.Journal of medical microbiology · 2025Article
- Dissemination of extended-spectrum beta-lactamase-producingMicrobial genomics · 2025Article
- High rate of multi-drug resistant Escherichia coli isolated from patients with urinary tract infections in Ifakara-Tanzania: implications for empirical antibiotic treatment guidelines and stewardship programs.Antimicrobial resistance and infection control · 2025Article
- Extended-Spectrum β-Lactamase-ProducingAntibiotics (Basel, Switzerland) · 2025Article
- High prevalence of fecal carriage of extended-spectrum beta-lactamase producingFrontiers in microbiology · 2024Article
- Extended-spectrum β-lactamase and carbapenemase producingFrontiers in microbiology · 2024Article
- Etiology of Fever and Associated Outcomes Among Adults Receiving Chemotherapy for the Treatment of Solid Tumors in Uganda.Open forum infectious diseases · 2023Article
- Incidence of ESBLs and carbapenemases among Enterobacterales and carbapenemases in Pseudomonas aeruginosa isolates collected globally: results from ATLAS 2017-2019.The Journal of antimicrobial chemotherapy · 2023Article
- Role of CTX-M-15 gene in spread of extended-spectrum beta-lactamases among immunocompetent patients in Ghana.African journal of laboratory medicine · 2023Article
- Emergence of New Delhi Metallo-International journal of microbiology · 2023Article
- Phenotypic and genotypic antibiotic susceptibility profiles of Gram-negative bacteria isolated from bloodstream infections at a referral hospital, Lusaka, Zambia.PLOS global public health · 2023Article
- Beta-lactamase resistance genes inAfrican journal of laboratory medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEnterobacteriaceae producing extended-spectrum beta-lactamases (ESBL) has been found all over the world, and risk factors for acquiring these bacteria involve hospital care and antibiotic treatment. Surveillance studies are present in Europe, North America, and Asia, but there is no summarizing research published on the situation in Africa.
aimThis review aims to describe the prevalence of ESBL-producing Enterobacteriaceae in hospital and community settings in Africa and the ESBL genes involved.
methodA non-systematic literature search was performed in PubMed. All articles published between 2008 and 2012 were screened and read in full text. Relevant articles were assessed for quality of evidence and included in the review. Articles were divided into regional areas in Africa and tabulated.
resultsESBL-producing Enterobacteriaceae in hospitalized patients and in communities varies largely between countries and specimens but is common in Africa. ESBLs (class A and D) and plasmid-encoded AmpC (pAmpC) were regularly found, but carbapenemases were also present.
conclusionESBL-producing Enterobacteriaceae in hospital and community settings in Africa is common. Surveillance of antimicrobial resistance needs to be implemented in Africa to tailor interventions targeted at stopping the dissemination of ESBL-producing Enterobacteriaceae.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.