Evidence map›Paper›PMID 24764788›Full record

ArticleGastroenterology & hepatology2013

Environmental influences on the onset and clinical course of Crohn's disease-part 1: an overview of external risk factors.

Aamir N Dam, Adam M Berg, Francis A Farraye

Open access · greenAbstract read
In one paragraph

Article in Gastroenterology & hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aamir N DamDr Dam is a medical resident in the Section of Internal Medicine, Dr Berg is a fellow in the Section of Gastroenterology, and Dr Farraye is the clinical director of the Section of Gastroenterology at Boston Medical Center in Boston, Massachusetts.
Adam M BergDr Dam is a medical resident in the Section of Internal Medicine, Dr Berg is a fellow in the Section of Gastroenterology, and Dr Farraye is the clinical director of the Section of Gastroenterology at Boston Medical Center in Boston, Massachusetts.
Francis A FarrayeDr Dam is a medical resident in the Section of Internal Medicine, Dr Berg is a fellow in the Section of Gastroenterology, and Dr Farraye is the clinical director of the Section of Gastroenterology at Boston Medical Center in Boston, Massachusetts.
Boston Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogenesis of Crohn's disease (CD) involves host, genetic, and environmental factors. These factors result in disturbances in the innate and adaptive immune systems and composition of the intestinal microbiota. Epidemiologic and migration studies support an environmental component in the development of CD. Environmental risk factors include childhood hygiene, air pollution, breastfeeding, smoking, diet, stress, exercise, seasonal variation, and appendectomy. This review, part 1 of a 2-part series, provides an overview of these external contributors to the development or exacerbation of CD. Part 2, which will be published in a subsequent issue, will discuss the influences of infections, vaccinations, and medications (including antibiotics, nonsteroidal anti-inflammatory agents, and oral contraceptives) on CD.

Indexed as

Crohn’s diseaseenvironmental factorsinfectioninflammatory bowel diseasemedicationspathogenesis

Identifiers

PMID24764788
PMCPMC3995193
OpenAlexW2129872820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.