ReviewBritish journal of sports medicine2014
Confounding factors and genetic polymorphism in the evaluation of individual steroid profiling.
Review in British journal of sports medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- Factors Confounding the Athlete Biological Passport: A Systematic Narrative Review.Sports medicine - open · 2021Pooled it
- Trial
- Acute Effects of Different Training Sessions on the Extended Blood Steroid Profile in Elite Male Football Players.Sports medicine (Auckland, N.Z.) · 2026Article
- Fragment-Resolved Carbon and Hydrogen Isotope Analysis of Urinary Steroids by Orbitrap Mass Spectrometry.Analytical chemistry · 2026Article
- The Evolution of Precision Anti-Doping From UGT2B17 Polymorphism Insights to Integrated Detection Frameworks.Drug testing and analysis · 2026Review
- Analysis of metabolic characteristics of epristeride in zebrafish based on LC-Q-TOF MS and its potential applications in doping control.RSC advances · 2026Article
- Improving the Determination of Carbon Isotope Ratios of Endogenous Steroids Found in Human Serum.Drug testing and analysis · 2025Article
- Advances in steroid purification for novel techniques in carbon isotope ratio mass spectrometry of doping control.RSC advances · 2025Review
- Steroid hormones in fish, caution for present and future: A review.Toxicology reports · 2024Review
- Dimethandrolone, a Potential Male Contraceptive Pill, is Primarily Metabolized by the Highly Polymorphic UDP-Glucuronosyltransferase 2B17 Enzyme in Human Intestine and Liver.Drug metabolism and disposition: the biological fate of chemicals · 2022Article
- Future opportunities for the Athlete Biological Passport.Frontiers in sports and active living · 2022Article
- Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport.Drug testing and analysis · 2021Article
- Current Insights into the Steroidal Module of the Athlete Biological Passport.International journal of sports medicine · 2021Review
- Carbon isotope ratios of endogenous steroids found in human serum-method development, validation, and reference population-derived thresholds.Analytical and bioanalytical chemistry · 2021Article
- The Specificities of Elite Female Athletes: A Multidisciplinary Approach.Life (Basel, Switzerland) · 2021Review
- Fighting Doping in Elite Sports: Blood for All Tests!Frontiers in sports and active living · 2019Article
- Geneticizing Ethnicity and Diet: Anti-doping Science and Its Social Impact in the Age of Post-genomics.Frontiers in genetics · 2017Article
- Antidoping programme and biological monitoring before and during the 2014 FIFA World Cup Brazil.British journal of sports medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the fight against doping, steroid profiling is a powerful tool to detect drug misuse with endogenous anabolic androgenic steroids. To establish sensitive and reliable models, the factors influencing profiling should be recognised. We performed an extensive literature review of the multiple factors that could influence the quantitative levels and ratios of endogenous steroids in urine matrix. For a comprehensive and scientific evaluation of the urinary steroid profile, it is necessary to define the target analytes as well as testosterone metabolism. The two main confounding factors, that is, endogenous and exogenous factors, are detailed to show the complex process of quantifying the steroid profile within WADA-accredited laboratories. Technical aspects are also discussed as they could have a significant impact on the steroid profile, and thus the steroid module of the athlete biological passport (ABP). The different factors impacting the major components of the steroid profile must be understood to ensure scientifically sound interpretation through the Bayesian model of the ABP. Not only should the statistical data be considered but also the experts in the field must be consulted for successful implementation of the steroidal module.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.