ArticleChembiochem : a European journal of chemical biology2014
An expanded set of fluorogenic sulfatase activity probes.
Article in Chembiochem : a European journal of chemical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Overview of Small Molecules as Fluorescent Probes ofACS omega · 2024Review
- Current methods to analyze lysosome morphology, positioning, motility and function.Traffic (Copenhagen, Denmark) · 2022Review
- Modified Enzyme Substrates for the Detection of Bacteria: A Review.Molecules (Basel, Switzerland) · 2020Review
- Supramolecular optimization of the visual contrast for colorimetric indicator assays that release resorufin dye.Chemical communications (Cambridge, England) · 2020Article
- Detection of bacterial sulfatase activity through liquid- and solid-phase colony-based assays.AMB Express · 2017Article
- Kinetic and optical properties of a new probe for sulfatase activity assay.Data in brief · 2017Article
- Small-Molecule Probes Reveal Esterases with Persistent Activity in Dormant and Reactivating Mycobacterium tuberculosis.ACS infectious diseases · 2016Article
- Profiling Esterases in Mycobacterium tuberculosis Using Far-Red Fluorogenic Substrates.ACS chemical biology · 2016Article
- Progress and prospects for small-molecule probes of bacterial imaging.Nature chemical biology · 2016Review
- Detection of Sulfatase Enzyme Activity with a CatalyCEST MRI Contrast Agent.Chemistry (Weinheim an der Bergstrasse, Germany) · 2016Article
- A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans.Journal of the American Chemical Society · 2015Article
- Chemiluminescent Probes for Imaging HChemical science · 2015Article
- Far-red fluorogenic probes for esterase and lipase detection.Chembiochem : a European journal of chemical biology · 2015Article
- Article
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Authors and funding
3 authors.
Funding
Abstract
Fluorogenic probes that are activated by an enzymatic transformation are ideally suited for profiling enzyme activities in biological systems. Here, we describe two fluorogenic enzyme probes, 3-O-methylfluorescein-sulfate and resorufin-sulfate, that can be used to detect sulfatases in mycobacterial lysates. Both probes were validated with a set of commercial sulfatases and used to reveal species-specific sulfatase banding patterns in a gel-resolved assay of mycobacterial lysates. The fluorogenic probes described here are suitable for various assays and provide a starting point for creating new sulfatase probes with improved selectivity for mycobacterial sulfatases.
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