Evidence map›Paper›PMID 24764070›Full record

Trial reportPhysical therapy2014

Pain sensitivity subgroups in individuals with spine pain: potential relevance to short-term clinical outcome.

Rogelio A Coronado, Joel E Bialosky, Michael E Robinson, Steven Z George

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physical therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Rogelio A CoronadoR.A. Coronado, PT, PhD, CSCS, FAAOMPT, Department of Physical Therapy, University of Florida, Box 100154, Gainesville, FL 32610-0154 (USA). rcoronado@phhp.ufl.edu szgeorge@phhp.ufl.edu.
Joel E BialoskyJ.E. Bialosky, PT, PhD, OCS, FAAOMPT, Department of Physical Therapy, University of Florida.
Michael E RobinsonM.E. Robinson, PhD, Department of Clinical and Health Psychology, University of Florida.
Steven Z GeorgeS.Z. George, PT, PhD, Department of Physical Therapy and Center for Pain Research and Behavioral Health, University of Florida, Box 100154, Gainesville, FL 32610-0154 (USA). rcoronado@phhp.ufl.edu szgeorge@phhp.ufl.edu.
University of Florida Health · USFPT University · VNUniversity of Florida · US

Funding

Rehabilitation Research Career Development ProgramK12HD055929 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BROWN, DAVID A · 2007 to 2021
$11.7M
Training In Rehabilitation and Neuromuscular PlasticityT32HD043730 · NICHD · UNIVERSITY OF FLORIDA · PI DAVID D FULLER · 2003 to 2026
$5.3M
NICHD NIH HHS K12 HD055929NICHD NIH HHS T32 HD043730
6 · The paper itself

Abstract

backgroundCluster analysis can be used to identify individuals similar in profile based on response to multiple pain sensitivity measures. There are limited investigations into how empirically derived pain sensitivity subgroups influence clinical outcomes for individuals with spine pain.

objectiveThe purposes of this study were: (1) to investigate empirically derived subgroups based on pressure and thermal pain sensitivity in individuals with spine pain and (2) to examine subgroup influence on 2-week clinical pain intensity and disability outcomes.

designA secondary analysis of data from 2 randomized trials was conducted.

methodsBaseline and 2-week outcome data from 157 participants with low back pain (n=110) and neck pain (n=47) were examined. Participants completed demographic, psychological, and clinical information and were assessed using pain sensitivity protocols, including pressure (suprathreshold pressure pain) and thermal pain sensitivity (thermal heat threshold and tolerance, suprathreshold heat pain, temporal summation). A hierarchical agglomerative cluster analysis was used to create subgroups based on pain sensitivity responses. Differences in data for baseline variables, clinical pain intensity, and disability were examined.

resultsThree pain sensitivity cluster groups were derived: low pain sensitivity, high thermal static sensitivity, and high pressure and thermal dynamic sensitivity. There were differences in the proportion of individuals meeting a 30% change in pain intensity, where fewer individuals within the high pressure and thermal dynamic sensitivity group (adjusted odds ratio=0.3; 95% confidence interval=0.1, 0.8) achieved successful outcomes. LIMITATIONS: Only 2-week outcomes are reported.

conclusionsDistinct pain sensitivity cluster groups for individuals with spine pain were identified, with the high pressure and thermal dynamic sensitivity group showing worse clinical outcome for pain intensity. Future studies should aim to confirm these findings.

Indexed as

AdolescentAdultCluster AnalysisDisability EvaluationFemaleHumansLow Back PainMaleMiddle AgedNeck PainPain MeasurementPain ThresholdSurveys and Questionnaires

Identifiers

PMID24764070
PMCPMC4118073
OpenAlexW2134546836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.