Evidence map›Paper›PMID 24763460›Full record

ArticleCirculation research2014

Cardiac alternans and ventricular fibrillation: a bad case of ryanodine receptors reneging on their duty.

Ariel L Escobar, Héctor H Valdivia

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Inhibition of CaPflugers Archiv : European journal of physiology · 2021
    Article
  3. Article
  4. Understanding Ca2+ alternans.The Journal of general physiology · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ariel L EscobarFrom the School of Engineering, Bioengineering Program, University of California-Merced (A.L.E.); and Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan-Ann Arbor (H.H.V.).
Héctor H Valdivia

Funding

RYANODINE RECEPTORS, Ca2+-TRIGGERED ARRHYTHMIAS AND HCMP01HL094291 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MOSS, RICHARD L · 2009 to 2013
$9.7M
Ryanodine Receptors, Calcium-dependent Arrhythmias & HCMR01HL055438 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VALDIVIA, HECTOR H · 1996 to 2023
$8.0M
Subcellular Origin of T-wave Alternans in the Beating Mouse HeartR01HL084487 · NHLBI · UNIVERSITY OF CALIFORNIA, MERCED · PI ESCOBAR, ARIEL L · 2007 to 2011
$1.9M
Cytosolic Calcium Sweeper in Cardiac MyocytesR01HL120108 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VALDIVIA, HECTOR H · 2014 to 2017
$1.5M
Calcins as Membrane-permeable Ligands of Ryanodine ReceptorsR01HL108175 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VALDIVIA, HECTOR H · 2011 to 2014
$1.4M
NHLBI NIH HHS P01 HL094291NHLBI NIH HHS P01-HL094291NHLBI NIH HHS R01 HL055438NHLBI NIH HHS R01-HL055438NHLBI NIH HHS R01 HL084487NHLBI NIH HHS R01-HL084487NHLBI NIH HHS R01 HL108175NHLBI NIH HHS R01 HL120108PHS HHS R01-108175
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Calcium SignalingRefractory Period, ElectrophysiologicalVoltage-Sensitive Dye ImagingAnimalsCalciumMyocytes, CardiacRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumVentricular FibrillationCalciumRyanodine Receptor Calcium Release ChannelEditorialsmyocardiumoptical restriction mappingryanodine receptor calcium release channel

Identifiers

PMID24763460
PMCPMC4040960

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.