ArticlePLoS neglected tropical diseases2014
Odorant and gustatory receptors in the tsetse fly Glossina morsitans morsitans.
Article in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 78 citations in OpenAlex.
- De novo genome assembly, annotation, and characterization of chemosensory genes in the camel ked (Hippobosca camelina).BMC genomics · 2025Article
- An Overview of Tsetse Fly Repellents: Identification and Applications.Journal of chemical ecology · 2024Review
- Identification of candidate chemosensory genes inFrontiers in physiology · 2024Article
- The genome of sheep ked (Melophagus ovinus) reveals potential mechanisms underlying reproduction and narrower ecological niches.BMC genomics · 2023Article
- Comparison of gut bacterial communities ofBiodiversity data journal · 2023Article
- Annotations of novel antennae-expressed genes in male Glossina morsitans morsitans tsetse flies.PloS one · 2022Article
- Perspectives on Odor-Based Control of Tsetse Flies in Africa.Frontiers in physiology · 2022Review
- Transmission of 'Candidatus Anaplasma camelii' to mice and rabbits by camel-specific keds, Hippobosca camelina.PLoS neglected tropical diseases · 2021Article
- Antennal Enriched Odorant Binding Proteins Are Required for Odor Communication inBiomolecules · 2021Article
- Comparative dissection of the peripheral olfactory system of the Chagas disease vectors Rhodnius prolixus and Rhodnius brethesi.PLoS neglected tropical diseases · 2021Article
- The Olfactory Chemosensation of Hematophagous Hemipteran Insects.Frontiers in physiology · 2021Review
- In silico-driven analysis of thePeerJ · 2021Article
- Expansions of chemosensory gene orthologs among selected tsetse fly species and their expressions in Glossina morsitans morsitans tsetse fly.PLoS neglected tropical diseases · 2020Article
- Genome of the webworm Hyphantria cunea unveils genetic adaptations supporting its rapid invasion and spread.BMC genomics · 2020Article
- Cellular and Molecular Targets of Waterbuck Repellent Blend Odors in Antennae ofFrontiers in cellular neuroscience · 2020Article
- Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes.Genome biology · 2019Article
- Responses of Glossina fuscipes fuscipes to visually attractive stationary devices baited with 4-methylguaiacol and certain repellent compounds in waterbuck odour.PLoS neglected tropical diseases · 2019Article
- Transcriptomics reveal the molecular underpinnings of chemosensory proteins in Chlorops oryzae.BMC genomics · 2018Article
- Using invertebrate model organisms for neuroscience research and training: an opportunity for Africa.Metabolic brain disease · 2018Article
- Enormous expansion of the chemosensory gene repertoire in the omnivorous German cockroach Blattella germanica.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2018Article
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Authors and funding
6 authors at 6 institutions in 3 countries.
Funding
Abstract
Tsetse flies use olfactory and gustatory responses, through odorant and gustatory receptors (ORs and GRs), to interact with their environment. Glossina morsitans morsitans genome ORs and GRs were annotated using homologs of these genes in Drosophila melanogaster and an ab initio approach based on OR and GR specific motifs in G. m. morsitans gene models coupled to gene ontology (GO). Phylogenetic relationships among the ORs or GRs and the homologs were determined using Maximum Likelihood estimates. Relative expression levels among the G. m. morsitans ORs or GRs were established using RNA-seq data derived from adult female fly. Overall, 46 and 14 putative G. m. morsitans ORs and GRs respectively were recovered. These were reduced by 12 and 59 ORs and GRs respectively compared to D. melanogaster. Six of the ORs were homologous to a single D. melanogaster OR (DmOr67d) associated with mating deterrence in females. Sweet taste GRs, present in all the other Diptera, were not recovered in G. m. morsitans. The GRs associated with detection of CO2 were conserved in G. m. morsitans relative to D. melanogaster. RNA-sequence data analysis revealed expression of GmmOR15 locus represented over 90% of expression profiles for the ORs. The G. m. morsitans ORs or GRs were phylogenetically closer to those in D. melanogaster than to other insects assessed. We found the chemoreceptor repertoire in G. m. morsitans smaller than other Diptera, and we postulate that this may be related to the restricted diet of blood-meal for both sexes of tsetse flies. However, the clade of some specific receptors has been expanded, indicative of their potential importance in chemoreception in the tsetse.
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