ArticleThe Journal of organic chemistry2014
Palladium-catalyzed hydroxylation of aryl and heteroaryl halides enabled by the use of a palladacycle precatalyst.
Article in The Journal of organic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Total Synthesis of (+)-CC-1065.Journal of the American Chemical Society · 2026Article
- Unlocking Catalyst Activation as a Critical Bottleneck in Cross-Coupling Reactions: Room-Temperature Couplings of Weak Nucleophiles Enabled by [Pd(1-MeNAP)TFA]Angewandte Chemie (International ed. in English) · 2026Article
- Article
- Iterative Catalyst-Controlled Diastereoselective Matteson Homologations Enable the Selective Synthesis of Benzestrol Isomers.Journal of the American Chemical Society · 2024Article
- Evolution of a Synthetic Strategy toward the Syntheses of Bis-tetrahydroisoquinoline Alkaloids.Accounts of chemical research · 2024Article
- Product Selectivity in Baeyer-Villiger Monooxygenase-Catalyzed Bacterial Alkaloid Core Structure Maturation.Journal of the American Chemical Society · 2024Article
- Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing.Acta pharmaceutica Sinica. B · 2024Review
- Deoxyfluorination of phenols for chemoselectiveNature protocols · 2023Review
- Site-Selective Cross-Coupling of Polyhalogenated Arenes and Heteroarenes with Identical Halogen Groups.Chemical reviews · 2022Review
- Site-Selective C-H Oxygenation via Aryl Sulfonium Salts.Angewandte Chemie (International ed. in English) · 2019Article
- Monophosphine Ligands Promote Pd-Catalyzed C-S Cross-Coupling Reactions at Room Temperature with Soluble Bases.ACS catalysis · 2019Article
- 2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET-Synthesis, Triage, and Radiolabeling.Molecules (Basel, Switzerland) · 2018Article
- Microwave-assisted green synthesis of anilines, phenols, and benzenediamines without transition metals, ligands, or organic solvents.Green chemistry letters and reviews · 2018Article
- Oxidative Addition Complexes as Precatalysts for Cross-Coupling Reactions Requiring Extremely Bulky Biarylphosphine Ligands.Organic letters · 2017Article
- Well-defined nickel and palladium precatalysts for cross-coupling.Nature reviews. Chemistry · 2017Article
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2 authors.
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Abstract
A method for the hydroxylation of aryl and heteroaryl halides, promoted by a catalyst based on a biarylphosphine ligand tBuBrettPhos (L5) and its corresponding palladium precatalyst (1), is described. The reactions allow the cross-coupling of both potassium and cesium hydroxides with (hetero)aryl halides to afford a variety of phenols and hydroxylated heteroarenes in high to excellent yield.
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