ArticleAmerican journal of pharmaceutical education2014
Application of genomic principles to pharmacotherapy of cancer.
Article in American journal of pharmaceutical education, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Pharmacogenomics Education Improves Pharmacy Student Perceptions of Their Abilities and Roles in Its Use.American journal of pharmaceutical education · 2018Article
- An Effective Approach to Teaching Pharmacogenomics in the First Year of Pharmacy Curriculum.American journal of pharmaceutical education · 2018Article
- Pharmacogenomics: From classroom to practice.Molecular genetics & genomic medicine · 2018Article
- Educational strategies to enable expansion of pharmacogenomics-based care.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2016Review
- Improving medical students' knowledge of genetic disease: a review of current and emerging pedagogical practices.Advances in medical education and practice · 2015Review
- Emerging roles for pharmacists in clinical implementation of pharmacogenomics.Pharmacotherapy · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo teach first-year (P1) pharmacy students to apply the principles of pharmacogenomics underlying clinical pharmacotherapeutics to cancer patients.
designUsing polymerase chain reaction (PCR) and high-resolution melting analysis of deoxyribonucleic acid (DNA) from colorectal cancer cell lines to determine the presence of somatic mutations for an oncogenic marker, students formulated the proper course of treatment for a patient with similar tumor genomics. ASSESSMENT: In a postintervention survey, students highly rated the effectiveness of the laboratory session for learning pharmacogenomics, and subsequent examination scores reflected retention of principles and understanding of clinical application.
conclusionThe pharmacogenomic laboratory exercise prepared students to understand how genetic markers give clinical insight into the appropriate application of drugs in oncology pharmacotherapy. Further, the session inspired their interest in learning more about pharmacogenomics and their professional roles in personalized medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.