ArticleG3 (Bethesda, Md.)2014
Genomic organization and evolution of the trace amine-associated receptor (TAAR) repertoire in Atlantic salmon (Salmo salar).
Article in G3 (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Genome-wide identification, expression analysis of taars (trace amine-associated receptors) and response to cadaverine and putrescine in Mandarin fish (Siniperca chuatsi).BMC genomics · 2025Article
- Revealing the evolutionary history and contemporary population structure of Pacific salmon in the Fraser River through genome resequencing.G3 (Bethesda, Md.) · 2024Article
- The genomic basis and environmental correlates of local adaptation in the Atlantic horse mackerel (Evolutionary applications · 2023Article
- Olfactory function in the trace amine-associated receptor family (TAARs) evolved twice independently.Scientific reports · 2021Article
- Olfactory signaling via trace amine-associated receptors.Cell and tissue research · 2021Review
- TAAR Agonists.Cellular and molecular neurobiology · 2020Review
- Differential expression of olfactory genes in Atlantic salmon (Ecology and evolution · 2019Article
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- Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture.BMC genomics · 2017Article
- Identification of olfactory receptor genes in the Japanese grenadier anchovyGenes & genomics · 2017Article
- From the Cover: Cadmium Exposure Differentially Alters Odorant-Driven Behaviors and Expression of Olfactory Receptors in Juvenile Coho Salmon (Oncorhynchus kisutch).Toxicological sciences : an official journal of the Society of Toxicology · 2016Article
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- Trace amine-associated receptors: ligands, neural circuits, and behaviors.Current opinion in neurobiology · 2015Review
- Evolutionary Conservation of 3-Iodothyronamine as an Agonist at the Trace Amine-Associated Receptor 1.European thyroid journal · 2015Article
- Identification and characterization of cichlid TAAR genes and comparison with other teleost TAAR repertoires.BMC genomics · 2015Article
- Analysis of human TAAR8 and murine Taar8b mediated signaling pathways and expression profile.International journal of molecular sciences · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is strong evidence that olfaction plays a key role in the homing of salmonids to their natal spawning grounds, particularly in the freshwater phase. However, the physiological and genetic mechanisms behind this biological phenomenon are largely unknown. It has been shown that Pacific salmon respond to dissolved free amino acids from their natal streams. This indicates that amino acids comprise part of the olfcatory cues for imprinting and homing in salmonids. As trace amine-associated receptors (TAARs), a class of olfactory receptors that are close relatives of the G protein-coupled aminergic neurotransmitter receptors, recognize amino acid metabolites, we hypothesize that TAARs play an important role in salmon homing by recognizing olfactory cues. Therefore, to better understand homing in Atlantic salmon, we set out to characterize the TAAR genes in this species. We searched the first assembly of the Atlantic salmon genome for sequences resembling TAARs previously characterized in other teleosts. We identified 27 putatively functional TAAR genes and 25 putative TAAR pseudogenes, which cluster primarily on chromosome 21 (Ssa21). Phylogenetic analysis of TAAR amino acid sequences from 15 vertebrate species revealed the TAAR gene family arose after the divergence of jawed and jawless vertebrates. The TAARs group into three classes with salmon possessing class I and class III TAARs. Within each class, evolution is characterized by species-specific gene expansions, which is in contrast to what is observed in other olfactory receptor families (e.g., OlfCs and oras).
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