ArticlePloS one2014
Arabidopsis thaliana glyoxalase 2-1 is required during abiotic stress but is not essential under normal plant growth.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Forewarned is forearmed: rice plants develop tolerance to post-anoxia during anoxic conditions by proteomic changes.Frontiers in plant science · 2025Article
- Article
- Glyoxalase I activity affects Arabidopsis sensitivity to ammonium nutrition.Plant cell reports · 2022Article
- Glyoxalase 2: Towards a Broader View of the Second Player of the Glyoxalase System.Antioxidants (Basel, Switzerland) · 2022Review
- Combined physiological and metabolomic analysis reveals the effects of different biostimulants on maize production and reproduction.Frontiers in plant science · 2022Article
- The metabolite methylglyoxal-mediated gene expression is associated with histone methylglyoxalation.Nucleic acids research · 2021Article
- Climate and Processing Effects on Tea (Molecules (Basel, Switzerland) · 2020Article
- 24-Epibrassinolide (EBR) Confers Tolerance against NaCl Stress in Soybean Plants by Up-Regulating Antioxidant System, Ascorbate-Glutathione Cycle, and Glyoxalase System.Biomolecules · 2019Article
- COI1-dependent jasmonate signalling affects growth, metabolite production and cell wall protein composition in arabidopsis.Annals of botany · 2018Article
- Interactive effect of 24-epibrassinolide and silicon alleviates cadmium stress via the modulation of antioxidant defense and glyoxalase systems and macronutrient content in Pisum sativum L. seedlings.BMC plant biology · 2018Article
- Genome-wide analysis and expression profiles of glyoxalase gene families in Chinese cabbage (Brassica rapa L).PloS one · 2018Article
- Defense against Reactive Carbonyl Species Involves at Least Three Subcellular Compartments Where Individual Components of the System Respond to Cellular Sugar Status.The Plant cell · 2017Article
- Differentially expressed genes during the imbibition of dormant and after-ripened seeds - a reverse genetics approach.BMC plant biology · 2017Article
- Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants.International journal of molecular sciences · 2017Review
- Characteristic Variations and Similarities in Biochemical, Molecular, and Functional Properties of Glyoxalases across Prokaryotes and Eukaryotes.International journal of molecular sciences · 2017Review
- Coordinated Actions of Glyoxalase and Antioxidant Defense Systems in Conferring Abiotic Stress Tolerance in Plants.International journal of molecular sciences · 2017Review
- Trait and Marker Associations inFrontiers in plant science · 2017Article
- Methylglyoxal: An Emerging Signaling Molecule in Plant Abiotic Stress Responses and Tolerance.Frontiers in plant science · 2016Review
- Transcriptional profiling in pearl millet (Pennisetum glaucum L.R. Br.) for identification of differentially expressed drought responsive genes.Physiology and molecular biology of plants : an international journal of functional plant biology · 2015Article
- Improved Salinity Tolerance in Carrizo Citrange Rootstock through Overexpression of Glyoxalase System Genes.BioMed research international · 2015Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The glyoxalase pathway, which consists of the two enzymes, GLYOXALASE 1 (GLX 1) (E.C.: 4.4.1.5) and 2 (E.C.3.1.2.6), has a vital role in chemical detoxification. In Arabidopsis thaliana there are at least four different isoforms of glyoxalase 2, two of which, GLX2-1 and GLX2-4 have not been characterized in detail. Here, the functional role of Arabidopsis thaliana GLX2-1 is investigated. Glx2-1 loss-of-function mutants and plants that constitutively over-express GLX2-1 resemble wild-type plants under normal growth conditions. Insilico analysis of publicly available microarray datasets with ATTEDII, Mapman and Genevestigator indicate potential role(s) in stress response and acclimation. Results presented here demonstrate that GLX2-1 gene expression is up-regulated in wild type Arabidopsis thaliana by salt and anoxia stress, and by excess L-Threonine. Additionally, a mutation in GLX2-1 inhibits growth and survival during abiotic stresses. Metabolic profiling studies show alterations in the levels of sugars and amino acids during threonine stress in the plants. Elevated levels of polyamines, which are known stress markers, are also observed. Overall our results suggest that Arabidopsis thaliana GLX2-1 is not essential during normal plant life, but is required during specific stress conditions.
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