Evidence map›Paper›PMID 24759725›Full record

ArticleJournal of clinical microbiology2014

Cross-infection of solid organ transplant recipients by a multidrug-resistant Klebsiella pneumoniae isolate producing the OXA-48 carbapenemase, likely derived from a multiorgan donor.

Tommaso Giani, Viola Conte, Salvatore Mandalà, Marco Maria D'Andrea, Francesco Luzzaro, Pier Giulio Conaldi, Paolo Grossi, Gian Maria Rossolini

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Perspective on donor-derived infections in Italy.Transplant infectious disease : an official journal of the Transplantation Society · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Fatal Donor-Derived Carbapenem-ResistantCase reports in transplantation · 2016
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Tommaso GianiDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Viola ConteDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Salvatore MandalàDepartment of Laboratory Medicine and Advanced Biotechnologies, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo, Italy UPMC, Palermo, Italy.
Marco Maria D'AndreaDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Francesco LuzzaroClinical Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy.
Pier Giulio ConaldiDepartment of Laboratory Medicine and Advanced Biotechnologies, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo, Italy RiMED foundation, Palermo, Italy.
Paolo GrossiDepartment of Surgical and Morphological Sciences, University of Insubria, Varese, Italy Clinical Infectious Diseases Unit, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
Gian Maria RossoliniDepartment of Medical Biotechnologies, University of Siena, Siena, Italy Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy Clinical Microbiology and Virology Unit, Department of Laboratory Medicine, Careggi University Hospital, Florence, Italy gianmaria.rossolini@unifi.it.
University of Siena · ITAlessandro Manzoni Hospital · ITRi.MED · ITUniversity of Florence · ITUniversity of Insubria · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe two cases of bacteremic infections caused by a multidrug-resistant Klebsiella pneumoniae isolate producing the OXA-48 carbapenemase that occurred in two solid organ transplant (liver and kidney) recipients, which was apparently transmitted with the allografts. This finding underscores the risk of donor-derived infections by multidrug-resistant Gram-negative pathogens in solid organ transplant recipients and emphasizes the need for rapid screening of organ donors for carriage of similar pathogens.

Indexed as

Drug Resistance, Multiple, BacterialAdultBacteremiabeta-LactamasesCross InfectionHumansKlebsiella InfectionsKlebsiella pneumoniaeMiddle AgedTransplantationTransplant RecipientsTransplantsbeta-Lactamasesoxacillinase

Identifiers

PMID24759725
PMCPMC4097706
OpenAlexW2095215813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.