ArticlePloS one2014
Meta-analytically informed network analysis of resting state FMRI reveals hyperconnectivity in an introspective socio-affective network in depression.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Role of the 5-HTThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Trial
- Synchrony Across Brains.Annual review of psychology · 2025Review
- Functional brain network organization and multidomain resilience to neighborhood disadvantage in youth.The American psychologist · 2024Article
- Activation Likelihood Estimation Neuroimaging Meta-Analysis: a Powerful Tool for Emotion Research.Psychology research and behavior management · 2024Review
- Opposing brain signatures of sleep in task-based and resting-state conditions.Nature communications · 2023Article
- Neural Basis of Internal Attention in Adults with Pure and Comorbid ADHD.Journal of attention disorders · 2023Article
- Altered effective connectivity in sensorimotor cortices is a signature of severity and clinical course in depression.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Brain areas associated with resilience to depression in high-risk young women.Brain structure & function · 2021Article
- Emotion processing and regulation in major depressive disorder: A 7T resting-state fMRI study.Human brain mapping · 2021Article
- Brain Networks Connectivity in Mild to Moderate Depression: Resting State fMRI Study with Implications to Nonpharmacological Treatment.Neural plasticity · 2021Article
- Age differences in predicting working memory performance from network-based functional connectivity.Cortex; a journal devoted to the study of the nervous system and behavior · 2020Article
- The Canadian Biomarker Integration Network in Depression (CAN-BIND): magnetic resonance imaging protocolsJournal of psychiatry & neuroscience : JPN · 2019Article
- Neuronal connectivity in major depressive disorder: a systematic review.Neuropsychiatric disease and treatment · 2018Review
- Bilateral Transcranial Magnetic Stimulation on DLPFC Changes Resting State Networks and Cognitive Function in Patients With Bipolar Depression.Frontiers in human neuroscience · 2018Article
- On the integrity of functional brain networks in schizophrenia, Parkinson's disease, and advanced age: Evidence from connectivity-based single-subject classification.Human brain mapping · 2017Article
- Resting-state test-retest reliability of a priori defined canonical networks over different preprocessing steps.Brain structure & function · 2017Article
- Altered neural connectivity in adult female rats exposed to early life social stress.Behavioural brain research · 2017Article
- Sharing self-related information is associated with intrinsic functional connectivity of cortical midline brain regions.Scientific reports · 2016Article
- Towards a second-person neuropsychiatry.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Transdiagnostic commonalities and differences in resting state functional connectivity of the default mode network in schizophrenia and major depression.NeuroImage. Clinical · 2016Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Alterations of social cognition and dysfunctional interpersonal expectations are thought to play an important role in the etiology of depression and have, thus, become a key target of psychotherapeutic interventions. The underlying neurobiology, however, remains elusive. Based upon the idea of a close link between affective and introspective processes relevant for social interactions and alterations thereof in states of depression, we used a meta-analytically informed network analysis to investigate resting-state functional connectivity in an introspective socio-affective (ISA) network in individuals with and without depression. Results of our analysis demonstrate significant differences between the groups with depressed individuals showing hyperconnectivity of the ISA network. These findings demonstrate that neurofunctional alterations exist in individuals with depression in a neural network relevant for introspection and socio-affective processing, which may contribute to the interpersonal difficulties that are linked to depressive symptomatology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.