Evidence map›Paper›PMID 24759063›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2014

Prevalence, incidence, and persistence of psychiatric and substance use disorders among mothers living with HIV.

Kathleen M Malee, Claude A Mellins, Yanling Huo, Katherine Tassiopoulos, Renee Smith, Patricia A Sirois, Susannah M Allison, Deborah Kacanek, Suad Kapetanovic, Paige L Williams and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01310023 (Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01310023 completednot on this map

Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women

TypeobservationalSponsorHarvard School of Public Health (HSPH)Ran2007 to 2025Enrolled5,169ConditionsAntiretroviral Toxicity
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Mental health, substance use, and risky sexual behaviors among women living with HIV.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Kathleen M Malee*Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL; †HIV Center for Clinical and Behavioral Studies, Division of Gender, Sexuality, and Health, New York State Psychiatric Institute and Columbia University, New York, NY; ‡Center for Biostatistics in AIDS Research, Department of Biostatistics, Harvard School of Public Health, Boston, MA; §Department of Epidemiology, Harvard School of Public Health, Boston, MA; ‖Department of Pediatrics, University of Illinois, Chicago, IL; ¶Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA; #National Institutes of Health/National Institute of Mental Health, Bethesda, MD; **Department of Psychiatry, Drexel University College of Medicine, Philadelphia, PA; ††Department of Children's Behavioral Health, Children's of Alabama, Birmingham, AL; and ‡‡Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY.
Claude A Mellins
Yanling Huo
Katherine Tassiopoulos
Renee Smith
Patricia A Sirois
Susannah M Allison
Deborah Kacanek
Suad Kapetanovic
Paige L Williams
Mitzie L Grant
Daniel Marullo
Angela A Aidala
Pediatric HIVAIDS Cohort Study (PHACS)
Harvard University Press · USColumbia University · USNational Institutes of Health · USChildren's of Alabama · USDrexel University · USInstitute of Behavioral Sciences · JPTulane University · USUniversity of Illinois Chicago · US

Funding

PHACS - Data and Operations CenterU01HD052102 · NICHD · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI WILLIAMS, PAIGE L · 2005 to 2019
$242.7M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Pediatric HIV/AIDS Cohort Study (PHACS): Understanding Maternal HIV Disease through Pregnancy and the Postpartum Period and its Role in Child Health OutcomesU01HD052104 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI VAN DYKE, RUSSELL B. · 2005 to 2019
$15.7M
Psychiatry Consultation Liaison Service ResearchZIAMH002922 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PAO, MARYLAND · 2009 to 2025
$11.5M
NCATS NIH HHS UL1 TR001082NICHD NIH HHS 3 U01 HD052102-05S1NICHD NIH HHS 3 U01 HD052102-06S3NICHD NIH HHS 3U01HD052104-06S1NICHD NIH HHS HD052102NICHD NIH HHS HD052104NICHD NIH HHS U01 HD052102NICHD NIH HHS U01 HD052104NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

objectiveTo evaluate prevalence, incidence, remission, and persistence of psychiatric and substance use disorders among HIV-infected mothers and identify biopsychosocial correlates.

methodsHIV-infected mothers (n = 1223) of HIV-exposed uninfected children enrolled in a prospective cohort study; HIV-uninfected mothers (n = 128) served as a comparison group. Mothers provided sociodemographic and health information and completed the Client Diagnostic Questionnaire (CDQ). Prevalence of any psychiatric or substance use disorder at initial evaluation was compared between the 2 groups. Incident, remitting, and persisting disorders were identified for 689 mothers with HIV who completed follow-up CDQs. We used logistic regression to evaluate adjusted associations of biopsychosocial characteristics with presence, incidence, remission, and persistence of disorders.

resultsThirty-five percent of mothers screened positive for any psychiatric or substance use disorder at initial evaluation, with no difference by maternal HIV status (P = 1.00). Among HIV-infected mothers, presence of any disorder was associated with younger age [adjusted odds ratio (aOR): 1.39; 95% CI: 1.09 to 1.75], single parenthood (aOR: 1.35; 95% CI: 1.08 to 1.68), and functional limitations (aOR: 2.29; 95% CI: 1.81 to 2.90). Incident disorders were associated with functional limitations (aOR: 1.92; 95% CI: 1.10 to 3.30). Among HIV-infected mothers with a disorder at initial evaluation (n = 238), 61% had persistent disorders. Persistent disorders were associated with lower income (aOR: 2.44; 95% CI: 1.33 to 4.76) and functional limitations (aOR: 3.19; 95% CI: 1.87 to 5.48). Receipt of treatment for any disorder was limited: 4.5% at study entry, 7% at follow-up, 5.5% at both entry and follow-up.

conclusionsPsychiatric and substance use disorders remain significant comorbid conditions among HIV-infected mothers and require accessible evidence-informed treatment.

Indexed as

MothersAdolescentAdultChildChild, PreschoolCohort StudiesFemaleHIV InfectionsHumansIncidenceInfantMaleMental DisordersPrevalenceRisk FactorsSurveys and Questionnaires

Identifiers

PMID24759063
PMCPMC3999478
OpenAlexW1977794314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.