ArticleChannels (Austin, Tex.)2014
Energetics of gating MscS by membrane tension in azolectin liposomes and giant spheroplasts.
Article in Channels (Austin, Tex.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2.Nature communications · 2024Article
- Pressure and ultrasound activate mechanosensitive TRAAK KbioRxiv : the preprint server for biology · 2023Article
- Cyclodextrins increase membrane tension and are universal activators of mechanosensitive channels.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- "Force-From-Lipids" mechanosensation in Corynebacterium glutamicum.Biophysical reviews · 2019Review
- Constitutive boost of a KProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Evolutionary specialization of MscCG, an MscS-like mechanosensitive channel, in amino acid transport in Corynebacterium glutamicum.Scientific reports · 2018Article
- Activation of the mechanosensitive ion channel MscL by mechanical stimulation of supported Droplet-Hydrogel bilayers.Scientific reports · 2017Article
- Influence of Global and Local Membrane Curvature on Mechanosensitive Ion Channels: A Finite Element Approach.Membranes · 2016Article
- Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension.Nature communications · 2016Article
- The evolutionary 'tinkering' of MscS-like channels: generation of structural and functional diversity.Pflugers Archiv : European journal of physiology · 2015Review
- Mechanosensitive gating of Kv channels.PloS one · 2015Review
- Biophysical implications of lipid bilayer rheometry for mechanosensitive channels.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- The effect of local bending on gating of MscL using a representative volume element and finite element simulation.Channels (Austin, Tex.) · 2014Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanosensitive (MS) ion channels are molecular sensors that detect and transduce signals across prokaryotic and eukaryotic cell membranes arising from external mechanical stimuli or osmotic gradients. They play an integral role in mechanosensory responses including touch, hearing, and proprioception by opening or closing in order to facilitate or prevent the flow of ions and organic osmolytes. In this study we use a linear force model of MS channel gating to determine the gating membrane tension (γ) and the gating area change (ΔA) associated with the energetics of MscS channel gating in giant spheroplasts and azolectin liposomes. Analysis of Boltzmann distribution functions describing the dependence of MscS channel gating on membrane tension indicated that the gating area change (ΔA) was the same for MscS channels recorded in both preparations. The comparison of the membrane tension (γ) gating the channel, however, showed a significant difference between the MscS channel activities in these two preparations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.