ArticleThe Journal of veterinary medical science2014
Decreased level of albumin in peripheral blood mononuclear cells of streptozotocin-induced diabetic rats.
Article in The Journal of veterinary medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- A novel rapid technique for quantifying serum oxidized albumin in a mouse model of chronic kidney disease.Journal of clinical biochemistry and nutrition · 2026Article
- Hypoglycemic Ability of Sericin-Derived Oligopeptides (SDOs) fromFoods (Basel, Switzerland) · 2024Article
- Chlorogenic acid attenuates pro-inflammatory response in the blood of streptozotocin-induced diabetic rats.Laboratory animal research · 2022Article
- Fruit Extract Derived from a Mixture of Noni, Pineapple and Mango Capable of Coagulating Milk and Producing Curd with Antidiabetic Activities.Food technology and biotechnology · 2022Article
- Albumin infusion ameliorates liver injury in streptozotocin-induced diabetic rats.Veterinarni medicina · 2022Article
- Effect of induced sublethal intoxication with neonicotinoid insecticides on Egyptian toads (Sclerophrys regularis).Environmental science and pollution research international · 2022Article
- Article
- Melatonin supplementation revives diabetic induced biochemical, histological and hematological impairments in rats.Heliyon · 2020Article
- A rapid method for measuring serum oxidized albumin in a rat model of proteinuria and hypertension.Scientific reports · 2019Article
- Selenium supplementation restores the decreased albumin level of peripheral blood mononuclear cells in streptozotocin-induced diabetic mice.The Journal of veterinary medical science · 2016Article
- Evaluation of Antidiabetic and Antihyperlipidemic Effects of Hydroalcoholic Extract of Leaves of Ocimum tenuiflorum (Lamiaceae) and Prediction of Biological Activity of its Phytoconstituents.Pharmacognosy researchArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the phenotypic level of albumin in peripheral blood mononuclear cells (PBMC) of streptozotocin (STZ)-induced diabetic rats. A specific reduction of albumin was identified by 2-dimensional electrophoresis and mass spectrometry. Decreased albumin content was also confirmed by immunoblotting and quantitative real-time PCR. Since albumin is a major and predominant antioxidant in plasma, the PBMC albumin may also contribute to their antioxidant activity. By measuring the amount of H2O2, lipid peroxidation and the redox form of glutathione, it was found that the production of the oxidative stress was elevated in STZ-diabetic rats compared to that of normal control. We suggest, therefore, that decreased albumin content may lead to the decreased antioxidant activity in the PBMC of type 1 diabetic rats.
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