ArticleDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2015
Cameron lesions in patients with hiatal hernias: prevalence, presentation, and treatment outcome.
Article in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Surgical management of hiatal hernia vs medical therapy to treat bleeding Cameron lesions: a systematic review and meta-analysis.Surgical endoscopy · 2021Pooled it
- Cameron Lesions: Endoscopic Characteristics, Clinical Profile, and Therapeutic Implications-A Retrospective Study of 43 Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Surgical repair of paraesophageal hernia resolves unexplained iron deficiency anemia in the vast majority of patients: a propensity-matched multicenter study.Surgical endoscopy · 2026Article
- A comprehensive endoscopic and clinical evaluation of Cameron ulcers: Insights from a single-center cross-sectional experience.Medicine · 2026Article
- The "ABCD" framework for assessment: a task-oriented approach to reconcile multimodal diagnostic discordance.Frontiers in medicine · 2026Review
- Article
- Gastric perforation secondary to incarcerated para-esophageal hiatal hernia in a French bulldog.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2023Article
- Laparoscopic hiatal hernia repair for treating patients with massive hiatal hernia and iron-deficiency anaemia.BMC surgery · 2023Article
- Rare causes of acute non-variceal upper gastrointestinal bleeding: A comprehensive review.World journal of gastroenterology · 2023Review
- Laparoscopic fundoplication for para-oesophageal hernia repair improves respiratory function in patients with dyspnoea: a prospective cohort study.Surgical endoscopy · 2022Article
- A 61-Year-Old Woman with Chronic Iron-Deficiency Anemia Due to a Cameron Lesion and a Response to Oral Application of Combined Poloxamer 407 with Hyaluronic Acid and Chondroitin Sulfate Following Single Treatment with Pantoprazole: A Case Report.The American journal of case reports · 2021Article
- Resolution of anemia and improved quality of life following laparoscopic hiatal hernia repair.Surgical endoscopy · 2020Article
- Cameron Ulcers: Rare Case of Overt Upper Gastrointestinal Bleed in a Patient with Alcohol Use Disorder.Cureus · 2020Article
- Laparoscopic repair of complete intrathoracic stomach with iron deficiency anemia: A case report.World journal of clinical cases · 2020Article
- Preoperative anemia: a common finding that predicts worse outcomes in patients undergoing primary hiatal hernia repair.Surgical endoscopy · 2019Article
- Radiofrequency Ablation of Cameron Lesions.Digestive diseases and sciences · 2017Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Cameron lesions, as defined by erosions and ulcerations at the diaphragmatic hiatus, are found in the setting of gastrointestinal (GI) bleeding in patients with a hiatus hernia (HH). The study aim was to determine the epidemiology and clinical manifestations of Cameron lesions. We performed a retrospective cohort study evaluating consecutive patients undergoing upper endoscopy over a 2-year period. Endoscopy reports were systematically reviewed to determine the presence or absence of Cameron lesions and HH. Inpatient and outpatient records were reviewed to determine prevalence, risk factors, and outcome of medical treatment of Cameron lesions. Of 8260 upper endoscopic examinations, 1306 (20.2%) reported an HH. When categorized by size, 65.6% of HH were small (<3 cm), 23.0% moderate (3-4.9 cm), and 11.4% were large (≥5 cm). Of these, 43 patients (mean age 65.2 years, 49% female) had Cameron lesions, with a prevalence of 3.3% in the presence of HH. Prevalence was highest with large HH (12.8%). On univariate analysis, large HH, frequent non-steroidal anti-inflammatory drug (NSAID) use, GI bleeding (both occult and overt), and nadir hemoglobin level were significantly greater with Cameron lesions compared with HH without Cameron lesions (P ≤ 0.03). Large HH size and NSAID use were identified as independent risk factors for Cameron lesions on multivariate logistic regression analysis. Cameron lesions are more prevalent in the setting of large HH and NSAID use, can be associated with GI bleeding, and can respond to medical management.
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Registered trials
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