Evidence map›Paper›PMID 24757674›Full record

Trial reportBioMed research international2014

Physical performance is associated with working memory in older people with mild to severe cognitive impairment.

K M Volkers, E J A Scherder

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06417034 (Hand Training Device For Cognitive Care), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06417034 nacompletednot on this mapstarted 2022, after this paper: background citation

Hand Training Device For Cognitive Care

TypeinterventionalSponsorNational Cheng-Kung University HospitalRan2022 to 2022Enrolled80ConditionsHealthy Elderly, Mild Cognitive Impairment (MCI)ArmsGame Software
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Higher VOScientific reports · 2021
    Trial
  2. Article
  3. Trajectory of Mobility Decline by Type of Dementia.Alzheimer disease and associated disorders
    Article
  4. Balance and Mobility as Predictors of Post-Stroke Cognitive Impairment.Dementia and geriatric cognitive disorders extra
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

K M VolkersDepartment of Clinical Neuropsychology, VU University, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands.
E J A ScherderDepartment of Clinical Neuropsychology, VU University, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands ; Center for Human Movement Sciences, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical performances and cognition are positively related in cognitively healthy people. The aim of this study was to examine whether physical performances are related to specific cognitive functioning in older people with mild to severe cognitive impairment.

methodsThis cross-sectional study included 134 people with a mild to severe cognitive impairment (mean age 82 years). Multiple linear regression was performed, after controlling for covariates and the level of global cognition, with the performances on mobility, strength, aerobic fitness, and balance as predictors and working memory and episodic memory as dependent variables.

resultsThe full models explain 49-57% of the variance in working memory and 40-43% of episodic memory. Strength, aerobic fitness, and balance are significantly associated with working memory, explaining 3-7% of its variance, irrespective of the severity of the cognitive impairment. Physical performance is not related to episodic memory in older people with mild to severe cognitive impairment.

conclusionsPhysical performance is associated with working memory in older people with cognitive impairment. Future studies should investigate whether physical exercise for increased physical performance can improve cognitive functioning. This trial is registered with ClinicalTrials.gov NTR1482.

Indexed as

Memory, EpisodicPhysical FitnessPsychomotor PerformanceAgedAged, 80 and overCognition DisordersCross-Sectional StudiesFemaleHumansMaleSeverity of Illness Index

Identifiers

PMID24757674
PMCPMC3971508

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.