Evidence map›Paper›PMID 24756070›Full record

ArticlePloS one2014

Investigating microRNA-target interaction-supported tissues in human cancer tissues based on miRNA and target gene expression profiling.

Wan J Hsieh, Feng-Mao Lin, Hsien-Da Huang, Hsiuying Wang

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Anti-NMDA Receptor Encephalitis and Vaccination.International journal of molecular sciences · 2017
    Article
  6. Article
  7. Noncoding RNA as regulators of cardiac fibrosis: current insight and the road ahead.Pflugers Archiv : European journal of physiology · 2016
    Review
  8. Article
  9. Article
  10. MicroRNA biology and pain.Progress in molecular biology and translational science · 2015
    Review
  11. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

4 authors.

Wan J HsiehInstitute of Statistics, National Chiao Tung University, Hsinchu, Taiwan.
Feng-Mao LinDepartment of Biological Science and Technology, Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan.
Hsien-Da HuangDepartment of Biological Science and Technology, Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan.
Hsiuying WangInstitute of Statistics, National Chiao Tung University, Hsinchu, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledRecent studies have revealed that a small non-coding RNA, microRNA (miRNA) down-regulates its mRNA targets. This effect is regarded as an important role in various biological processes. Many studies have been devoted to predicting miRNA-target interactions. These studies indicate that the interactions may only be functional in some specific tissues, which depend on the characteristics of an miRNA. No systematic methods have been established in the literature to investigate the correlation between miRNA-target interactions and tissue specificity through microarray data. In this study, we propose a method to investigate miRNA-target interaction-supported tissues, which is based on experimentally validated miRNA-target interactions. The tissue specificity results by our method are in accordance with the experimental results in the literature. AVAILABILITY AND IMPLEMENTATION: Our analysis results are available at http://tsmti.mbc.nctu.edu.tw/ and http://www.stat.nctu.edu.tw/hwang/tsmti.html.

Indexed as

Gene Expression ProfilingGene Expression Regulation, NeoplasticRNA InterferenceAlgorithmsCluster AnalysisComputational BiologyDatabases, Nucleic AcidHumansInternetMicroRNAsNeoplasmsRNA, MessengerTissue BanksMicroRNAsRNA, Messenger

Identifiers

PMID24756070
PMCPMC3995724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.