Evidence map›Paper›PMID 24755927›Full record

ArticleEuropean journal of clinical nutrition2014

The effects of Ramadan fasting on endothelial function in patients with cardiovascular diseases.

B Yousefi, Z Faghfoori, N Samadi, H Karami, Y Ahmadi, R Badalzadeh, V Shafiei-Irannejad, M Majidinia, H Ghavimi, M Jabbarpour

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Article in European journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Religiously Conditioned Health Behaviors within Selected Religious Traditions.International journal of environmental research and public health · 2022
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Asymmetric dimethylarginine and Ramadan fasting.European journal of clinical nutrition · 2014
    Article
  16. Article
  17. The cardiac patient in Ramadan.Avicenna journal of medicine
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

B Yousefi1] Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran [2] Students' Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran [3] Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Z Faghfoori1] Students' Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran [2] Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.
N Samadi1] Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran [2] Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
H KaramiDepartment of Biotechnology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
Y AhmadiDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
R BadalzadehDepartment of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
V Shafiei-IrannejadDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
M MajidiniaDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
H GhavimiDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
M JabbarpourDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Tabriz University of Medical Sciences · IRArak University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesEndothelial dysfunction, which can be manifested by loss of nitric oxide bioavailability, is an increasingly recognized cause of cardiovascular diseases. Previous studies showed that diets affect endothelial function and modify cardiovascular risks. This study aimed to assess the effects of Ramadan fasting, as a diet intervention, on endothelial function. SUBJECTS/

methodsThe study population consisted of 21 male patients (mean age: 52±9 years) with cardiovascular risks (coronary artery disease, cerebrovascular or peripheral arterial diseases). The biochemical variables in serum of patients were measured 2 days before and after Ramadan fasting. The levels of asymmetric dimethylarginine (ADMA) and vascular endothelial growth factor (VEGF) were evaluated using the enzyme-linked immunosorbent assay. Nitric oxide (NO) and Malondialdehyde (MDA) levels were measured by the Griess and thiobarbituric acid reaction substances assay, respectively.

resultsNO levels in patients after Ramadan fasting were significantly higher compared with the baseline value (85.1±11.54 vs 75.8±10.7 μmol/l) (P<0.05). Post-Ramadan levels of ADMA decreased significantly in comparison with pre-Ramadan levels (802.6±60.9 vs 837.6±51.0 nmol/l) (P<0.05). In addition, the levels of VEGF and MDA changed during Ramadan fasting, but these changes were not statistically significant (228.1±27.1 vs 222.7±22.9 pg/ml and 3.2±0.7 vs 3.6±1.1 μmol/l, respectively).

conclusionsRamadan fasting may have beneficial effects on endothelial function and can modulate cardiovascular risks. Further studies are needed to confirm the clinical significance of Ramadan fasting on cardiovascular health.

Indexed as

AdultArginineCardiovascular DiseasesCerebrovascular DisordersCoronary Artery DiseaseEndothelium, VascularFastingHumansIslamMaleMalondialdehydeMiddle AgedNitric OxidePeripheral Arterial DiseaseVascular Endothelial Growth Factor AArginineMalondialdehydeNitric OxideN,N-dimethylarginineVascular Endothelial Growth Factor A

Identifiers

PMID24755927
OpenAlexW2005087958

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.