Evidence map›Paper›PMID 24755769›Full record

ArticlePloS one2014

Emergence of collective territorial defense in bacterial communities: horizontal gene transfer can stabilize microbiomes.

János Juhász, Attila Kertész-Farkas, Dóra Szabó, Sándor Pongor

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Role of horizontal gene transfer and cooperation in rhizosphere microbiome assembly.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

János JuhászFaculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.
Attila Kertész-FarkasGroup of Protein Structure and Bioinformatics, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.
Dóra SzabóInstitute of Medical Microbiology, Semmelweis University, Budapest, Hungary.
Sándor PongorFaculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary; Group of Protein Structure and Bioinformatics, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multispecies bacterial communities such as the microbiota of the gastrointestinal tract can be remarkably stable and resilient even though they consist of cells and species that compete for resources and also produce a large number of antimicrobial agents. Computational modeling suggests that horizontal transfer of resistance genes may greatly contribute to the formation of stable and diverse communities capable of protecting themselves with a battery of antimicrobial agents while preserving a varied metabolic repertoire of the constituent species. In other words horizontal transfer of resistance genes makes a community compatible in terms of exoproducts and capable to maintain a varied and mature metagenome. The same property may allow microbiota to protect a host organism, or if used as a microbial therapy, to purge pathogens and restore a protective environment.

Indexed as

Gene Transfer, HorizontalBacteriaComputer SimulationGenetic VariationGenotypeMicrobiotaModels, Biological

Identifiers

PMID24755769
PMCPMC3995721

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.