Evidence map›Paper›PMID 24755151›Full record

ReviewJournal of the American Heart Association2014

Cancer therapy-induced cardiotoxicity: basic mechanisms and potential cardioprotective therapies.

Virginia Shalkey Hahn, Daniel J Lenihan, Bonnie Ky

Abstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Guideline
  4. Pooled it
  5. Trial
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  12. Adverse drug reactions associated with doxorubicin and epirubicin: A descriptive analysis from VigiBase.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2026
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81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Virginia Shalkey HahnDepartment of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Daniel J Lenihan
Bonnie Ky

Funding

Multimarker Risk Prediction in Cancer Therapy CardiotoxicityR01HL118018 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KY, BONNIE · 2014 to 2018
$3.7M
The Role of Neuregulin in Human Cardiac Remodeling and Heart FailureK23HL095661 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KY, BONNIE · 2010 to 2014
$704k
NHLBI NIH HHS K23 HL095661NHLBI NIH HHS R01 HL118018
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Exercise TherapyAnimalsAntineoplastic AgentsCytoprotectionHeart DiseasesHumansMolecular Targeted TherapyMyocardiumProtective AgentsRisk AssessmentRisk FactorsSignal TransductionTreatment OutcomeAntineoplastic AgentsProtective Agentsanthracycline cardiotoxicitycardio‐oncologycardiotoxicitysunitinib cardiotoxicitytrastuzumab cardiotoxicity

Identifiers

PMID24755151
PMCPMC4187516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.