ReviewAnnals of the American Thoracic Society2014
Interstitial lung disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.
Review in Annals of the American Thoracic Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06534528 (An Open Clinical Study Exploring the Safety, Tolerability, and Preliminary Efficacy of Human Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Interstitial Lung Disease), which is not on this map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Open Clinical Study Exploring the Safety, Tolerability, and Preliminary Efficacy of Human Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Interstitial Lung Disease (ILD)
Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Targeting ferroptosis as a vulnerability in pulmonary diseases.Cell death & disease · 2022Review
- An epigenome-wide study of DNA methylation profiles and lung function among American Indians in the Strong Heart Study.Clinical epigenetics · 2022Article
- Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1Acta pharmaceutica Sinica. B · 2022Article
- Clinical Relevance and Management of "Pre-Interstitial Lung Disease".Clinics in chest medicine · 2021Review
- Update in Interstitial Lung Disease 2020.American journal of respiratory and critical care medicine · 2021Review
- Article
- Longitudinal micro-computed tomography-derived biomarkers quantify non-resolving lung fibrosis in a silicosis mouse model.Scientific reports · 2020Article
- Reference values for high attenuation areas on chest CT in a healthy, never-smoker, multi-ethnic sample: The MESA study.Respirology (Carlton, Vic.) · 2020Article
- Evaluation of integrin αvβNature communications · 2019Article
- Circulating adhesion molecules and subclinical interstitial lung disease: the Multi-Ethnic Study of Atherosclerosis.The European respiratory journal · 2019Article
- Rice Consumption and Subclinical Lung Disease in US Adults: Observational Evidence From the Multi-Ethnic Study of Atherosclerosis.American journal of epidemiology · 2019Article
- Interstitial lung abnormalities: erecting fences in the path towards advanced pulmonary fibrosis.Thorax · 2019Review
- The Role of TGF-β Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis.International journal of molecular sciences · 2018Review
- Serum 25-Hydroxyvitamin D Concentrations Are Associated with Computed Tomography Markers of Subclinical Interstitial Lung Disease among Community-Dwelling Adults in the Multi-Ethnic Study of Atherosclerosis (MESA).The Journal of nutrition · 2018Article
- Article
- High-Attenuation Areas on Chest Computed Tomography and Clinical Respiratory Outcomes in Community-Dwelling Adults.American journal of respiratory and critical care medicine · 2017Article
- The Objective Identification and Quantification of Interstitial Lung Abnormalities in Smokers.Academic radiology · 2017Article
- Raising awareness of bronchiectasis in primary care: overview of diagnosis and management strategies in adults.NPJ primary care respiratory medicine · 2017Review
- Broad Therapeutic Efficacy of Nintedanib in Idiopathic Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2016Article
- Detection of Rheumatoid Arthritis-Interstitial Lung Disease Is Enhanced by Serum Biomarkers.American journal of respiratory and critical care medicine · 2015Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 1 country.
Funding
Abstract
Population-based, longitudinal studies spanning decades linking risk factors in childhood, adolescence and early adulthood to incident clinical interstitial lung disease (ILD) events in late adulthood have not been performed. In addition, no observational or randomized clinical trials have been conducted; therefore, there is presently no evidence to support the notion that reduction of risk factor levels in early life prevents ILD events in adult life. Primary prevention strategies are host-directed interventions designed to modify adverse risk factors (i.e., smoking) with the goal of preventing the development of ILD, whereas primordial prevention for ILD can be defined as the elimination of external risk factors (i.e., environmental pollutants). As no ILD primary prevention studies have been previously conducted, we propose that research studies that promote implementation of primary prevention strategies could, over time, make a subset of ILD preventable. Herein, we provide a number of initial steps required for the future implementation of prevention strategies; this statement discusses the rationale and available evidence that support potential opportunities for primordial and primary prevention, as well as fertile areas for future research of preventive intervention in ILD.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.