ArticleHistochemistry1989
Co-localization of chromogranin A and B, secretogranin II and neuropeptide Y in chromaffin granules of rat adrenal medulla studied by electron microscopic immunocytochemistry.
Article in Histochemistry, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 55 citations in OpenAlex.
- Article
- Chromogranin B (CHGB) is dimorphic and responsible for dominant anion channels delivered to cell surface via regulated secretion.Frontiers in molecular neuroscience · 2023Article
- Differential Expression of Secretogranins II and III in Canine Adrenal Chromaffin Cells and Pheochromocytomas.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2022Article
- Lumenal protein within secretory granules affects fusion pore expansion.Biophysical journal · 2014Article
- Protein mobility within secretory granules.Biophysical journal · 2014Article
- Beta cell chromogranin B is partially segregated in distinct granules and can be released separately from insulin in response to stimulation.Diabetologia · 2008Article
- Differential dynamics of Rab3A and Rab27A on secretory granules.Journal of cell science · 2007Article
- Near simultaneous release of classical and peptide cotransmitters from chromaffin cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- Effects of secretogranin II-derived peptides on the release of neurotransmitters monitored in the basal ganglia of the rat with in vivo microdialysis.Naunyn-Schmiedeberg's archives of pharmacology · 1996Article
- Immunohistochemical localization of bioactive peptides and amines associated with the chromaffin tissue of five species of fish.Cell and tissue research · 1995Article
- The granin protein family: markers for neuroendocrine cells and tools for the diagnosis of neuroendocrine tumors.Journal of endocrinological investigation · 1994Review
- The chromogranins A and B: the first 25 years and future perspectives.Neuroscience · 1992Review
- Distribution and ontogeny of chromogranin A and tyrosine hydroxylase in the carotid body and glomus cells located in the wall of the common carotid artery and its branches in the chicken.Histochemistry · 1990Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The co-localization of various antigens in rat chromaffin granules was investigated by the immunogold staining procedure. In ultrathin serial sections staining of chromaffin granules was obtained with antisera against chromogranin A, chromogranin B, secretogranin II and neuropeptide Y. These results indicated that these antigens are costored within chromaffin granules. To further corroborate this point a double immunogold staining procedure was used. This method unequivocally established that chromogranin A, chromogranin B, secretogranin II and neuropeptide Y are co-localized in the same chromaffin granules. These results are relevant for studies demonstrating changes in the level of these peptides in adrenal medulla. The co-localization makes it likely that such changes lead to a different relative composition of the secretory quanta of chromaffin granules.
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