Evidence map›Paper›PMID 24754475›Full record

ReviewCell communication & adhesion2014

Force measurement tools to explore cadherin mechanotransduction.

Sarah C Stapleton, Anant Chopra, Christopher S Chen

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell communication & adhesion, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. A toolbox to explore the mechanics of living embryonic tissues.Seminars in cell & developmental biology · 2016
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sarah C StapletonDepartment of Chemical and Biomolecular Engineering, University of Pennsylvania , Philadelphia, PA , USA.
Anant Chopra
Christopher S Chen
Boston University · USUniversity of Pennsylvania · US

Funding

REGULATION OF ANGIOGENESIS BY MICROENVIRONMENTAL CUESR01EB000262 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI CHEN, CHRISTOPHER S · 2002 to 2023
$6.2M
Cadherins, integrins, and mechanochemical signalingR01HL073305 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHEN, CHRISTOPHER S · 2003 to 2011
$3.4M
NHLBI NIH HHS R01 HL073305NIBIB NIH HHS R01 EB000262
6 · The paper itself

Abstract

Cell-cell adhesions serve to mechanically couple cells, allowing for long-range transmission of forces across cells in development, disease, and homeostasis. Recent work has shown that such contacts also play a role in transducing mechanical cues into a wide variety of cellular behaviors important to tissue function. As such, understanding the mechanical regulation of cells through their adhesion molecules has become a point of intense focus. This review will highlight the existing and emerging technologies and models that allow for exploration of cadherin-based adhesions as sites of mechanotransduction.

Indexed as

Mechanotransduction, CellularCadherinsCell AdhesionHumansCadherinsadherens junctionscadherinscell adhesionsforce transductionmechanotransductiontraction force microscopy

Identifiers

PMID24754475
PMCPMC7079283
OpenAlexW2011263220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.