Evidence map›Paper›PMID 24754044›Full record

Trial reportDepression and anxiety2014

Exercise improves sexual function in women taking antidepressants: results from a randomized crossover trial.

Tierney Ahrold Lorenz, Cindy May Meston

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Depression and anxiety, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Assessing the effect ofFrontiers in psychiatry · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. The impact of severe mental disorders and psychotropic medications on sexual health and its implications for clinical management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Lifestyle Choices Can Augment Female Sexual Well-Being.American journal of lifestyle medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Tierney Ahrold Lorenz
Cindy May Meston
Indiana University Bloomington · USThe University of Texas at Austin · US

Funding

Common Themes in Reproductive DiversityT32HD049336 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI DALE R SENGELAUB · 2005 to 2026
$4.4M
Effects of Early Abuse on Adult Intimate RelationshipsR01HD051676 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI MESTON, CINDY M · 2006 to 2010
$960k
Efficacy of an Acute Exercise Intervention for Side Effects of SSRIsF31MH085416 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI LORENZ, TIERNEY KYLE AHROLD · 2009 to 2011
$106k
NICHD NIH HHS R01 HD051676NICHD NIH HHS T32 HD049336NICHD NIH HHS T32HD049336NIMH NIH HHS F31 MH085416NIMH NIH HHS F31MH085416
6 · The paper itself

Abstract

backgroundIn laboratory studies, exercise immediately before sexual stimuli improved sexual arousal of women taking antidepressants [1]. We evaluated if exercise improves sexual desire, orgasm, and global sexual functioning in women experiencing antidepressant-induced sexual side effects.

methodsFifty-two women who were reporting antidepressant sexual side effects were followed for 3 weeks of sexual activity only. They were randomized to complete either three weeks of exercise immediately before sexual activity (3×/week) or 3 weeks of exercise separate from sexual activity (3×/week). At the end of the first exercise arm, participants crossed to the other. We measured sexual functioning, sexual satisfaction, depression, and physical health.

resultsExercise immediately prior to sexual activity significantly improved sexual desire and, for women with sexual dysfunction at baseline, global sexual function. Scheduling regular sexual activity significantly improved orgasm function; exercise did not increase this benefit. Neither regular sexual activity nor exercise significantly changed sexual satisfaction.

conclusionsScheduling regular sexual activity and exercise may be an effective tool for the behavioral management of sexual side effects of antidepressants

Indexed as

Personal SatisfactionAdultAntidepressive Agents, Second-GenerationCross-Over StudiesExerciseExercise TherapyFemaleHumansSelective Serotonin Reuptake InhibitorsSexual BehaviorSexual Dysfunction, PhysiologicalSingle-Blind MethodTime FactorsTreatment OutcomeAntidepressive Agents, Second-GenerationSelective Serotonin Reuptake Inhibitors

Identifiers

PMID24754044
PMCPMC4039497
OpenAlexW2155855707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.