Evidence map›Paper›PMID 24753893›Full record

ArticleFacts, views & vision in ObGyn2012

High susceptibility to cytomegalovirus infection of pregnant women in Flanders, Belgium.

E Leuridan, M Ieven, N Hens, P Van Damme

Open access · greenAbstract read
In one paragraph

Article in Facts, views & vision in ObGyn, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

E LeuridanCentre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Universiteitsplein, 1a, 2610 Wilrijk, Antwerp, Belgium.
M IevenDepartment of Medical Microbiology, Vaccine and Infectious Disease Institute, Faculty of Medicine, University of Antwerp.
N HensInteruniversity Institute for Biostatistics and statistical Bioinformatics, Hasselt University, Campus Diepenbeek, Agoralaan 1, 3590 Diepenbeek & CHERMID, Vaccine and Infectious Disease Institute, Faculty of Medicine, University of Antwerp.
P Van DammeCentre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Universiteitsplein, 1a, 2610 Wilrijk, Antwerp, Belgium.
Infectious Diseases Institute · UGHasselt University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternal antibodies against cytomegalovirus (CMV) infection offer, to some extent, protection against congenital CMV infection. This study describes the seroprevalence of CMV-specific IgG in 220 parturient women during pregnancy, at delivery, at 3 months after delivery and in their cord blood (Flanders, Belgium, 2006-2008). ELISA was used to measure IgG. Of this population, 30% had positive IgG titres. Active transplacental transport was confirmed with a ratio 1.15/1. Elevated maternal IgG titre and increased parity, but not age, were significantly associated with higher seroprevalence of CMV-specific IgG in the cord blood. These data indicate a high susceptibility to CMV among fertile women. Prenatal prevention and other strategies to prevent intra-uterine infection are of critical importance in a highly susceptible population.

Indexed as

Cord bloodcytomegalovirusmaternal antibodiespregnancyseroprevalencetransplacental transport

Identifiers

PMID24753893
PMCPMC3987497
OpenAlexW1934365548

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.