Evidence map›Paper›PMID 24753744›Full record

ArticleInternational journal of clinical and experimental medicine2014

Exploratory study of oral mucosal colonization of human gastric Helicobacter pylori in mice.

Xueqin Wan, Dongsheng Tang, Xiaohuan Zhang, Hongming Li, Zhixin Cui, Sijuan Hu, Ming Huang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xueqin WanDepartment of Pathogenic Microbiology, Foshan University Foshan, Guangdong, 528000, China.
Dongsheng TangDepartment of Pathogenic Microbiology, Foshan University Foshan, Guangdong, 528000, China.
Xiaohuan ZhangGuanghua School of Stomatology, Sun Yat-Sen University Guangzhou, Guangdong, 510000, China.
Hongming LiDepartment of Pathogenic Microbiology, Foshan University Foshan, Guangdong, 528000, China.
Zhixin CuiDepartment of Pathogenic Microbiology, Foshan University Foshan, Guangdong, 528000, China.
Sijuan HuDepartment of Gastroenterology, Xijing Hospital Xi'an, 710032, China.
Ming HuangDepartment of Pathogenic Microbiology, Foshan University Foshan, Guangdong, 528000, China.
Foshan University · CNSun Yat-sen University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, human gastric Helicobacter pylori (Hp) was closely attached to the pre-treated mouse buccal mucosa by using artificial oral film to induce the growth and colonization of Hp on the buccal mucosa in mice. Sixty BALB/c mice were divided into three groups, in which Hp biofilm colonization was detected in three mice in Hp film group (Hp mesh biofilm accumulation under an optical microscope; Hp accumulated colonization under an electron microscope). There were no Hp biofilms detected in Hp smear group or the control group with black film. In this study, human gastric Hp was first used to artificially induce the growth and colonization of Hp on the buccal mucosa in mice. The mouse model of oral infection with Hp was initially established, providing animal experimental evidences for oral conditions of growth and colonization of Hp on the buccal mucosa in mice, and providing a workable animal modeling method for further research of joint infection of Hp on the mouth and stomach, as well as the relationship between oral Hp and gastric Hp.

Indexed as

Helicobacter pylorimouse modeloral colonization

Identifiers

PMID24753744
PMCPMC3992389
OpenAlexW2204134048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.