Evidence map›Paper›PMID 24753659›Full record

ArticleAnnals of Indian Academy of Neurology2014

Alzheimer disease: An interactome of many diseases.

Balaji S Rao, Krishna Kant Gupta, Pujitha Karanam, Anusha Peruri

Open access · diamondAbstract read
In one paragraph

Article in Annals of Indian Academy of Neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Balaji S RaoDepartment of Bioinformatics, NTHRYS Biotech Labs, Hyderabad, Andhra Pradesh, India.
Krishna Kant GuptaDepartment of Bioinformatics, NTHRYS Biotech Labs, Hyderabad, Andhra Pradesh, India.
Pujitha KaranamDepartment of Bioinformatics, NTHRYS Biotech Labs, Hyderabad, Andhra Pradesh, India.
Anusha PeruriDepartment of Bioinformatics, NTHRYS Biotech Labs, Hyderabad, Andhra Pradesh, India.
Biotech Park · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer Disease (AD) is an outcome as well as source of many diseases. Alzheimer is linked with many other diseases like Diabetes type 2, cholesterolemia, hypertension and many more. But how each of these diseases affecting other is still unknown to scientific community. Signaling Pathways of one disease is interlinked with other disease. But to what extent healthy brain is affected when any signaling in human body is disturbed is the question that matters. There is a need of Pathway analysis, Protein-Protein interaction (PPI) and the conserved interactome study in AD and linked diseases. It will be helpful in finding the potent drug or vaccine target in conscious manner. In the present research the Protein-Protein interaction of all the proteins involved in Alzheimer Disease is analyzed using ViSANT and osprey tools and pathway analysis further reveals the significant genes/proteins linking AD with other diseases.

Indexed as

Alzheimer diseasecentralitygene set enrichment analysisnetwork analysisprotein-protein interactionsreactive oxygen speciesstring

Identifiers

PMID24753659
PMCPMC3992769
OpenAlexW2080509092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.