ArticleProceedings of the National Academy of Sciences of the United States of America2014
Establishing the validity of domestication genes using DNA from ancient chickens.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45 citing papers in PubMed.
- Ancient DNA unravels the history of chickens in the Baltic Sea region and the continuity of landrace lineages.Heredity · 2026Article
- Genetic assessment and Identification of genes related to characterization of Guangdong local goose breeds based on modern and historical genomes.Communications biology · 2025Article
- Signals of selection and ancestry in independently feral Gallus gallus populations.Molecular ecology · 2024Article
- Unraveling the diversity and cultural heritage of fruit crops through paleogenomics.Trends in genetics : TIG · 2024Review
- Archaeological and molecular evidence for ancient chickens in Central Asia.Nature communications · 2024Article
- Significant genomic introgression from grey junglefowl (Gallus sonneratii) to domestic chickens (Gallus gallus domesticus).Journal of animal science and biotechnology · 2024Article
- The mammalian brain under domestication: Discovering patterns after a century of old and new analyses.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2022Review
- The biocultural origins and dispersal of domestic chickens.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Origin of the domestic chicken from modern biological and zooarchaeological approaches.Animal frontiers : the review magazine of animal agriculture · 2021Article
- Article
- Estimation of Natural Selection and Allele Age from Time Series Allele Frequency Data Using a Novel Likelihood-Based Approach.Genetics · 2020Article
- Animal domestication in the era of ancient genomics.Nature reviews. Genetics · 2020Review
- 863 genomes reveal the origin and domestication of chicken.Cell research · 2020Article
- European and Asian contribution to the genetic diversity of mainland South American chickens.Royal Society open science · 2020Article
- Accumulation of genetic variants associated with immunity in the selective breeding of broilers.BMC genetics · 2020Article
- Were domestic camelids present on the prehispanic South American agricultural frontier? An ancient DNA study.PloS one · 2020Article
- Avian Physiology: Are Birds Simply Feathered Mammals?Frontiers in physiology · 2020Review
- No "doom" in chicken domestication?PLoS genetics · 2019Article
- The broiler chicken as a signal of a human reconfigured biosphere.Royal Society open science · 2018Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Modern domestic plants and animals are subject to human-driven selection for desired phenotypic traits and behavior. Large-scale genetic studies of modern domestic populations and their wild relatives have revealed not only the genetic mechanisms underlying specific phenotypic traits, but also allowed for the identification of candidate domestication genes. Our understanding of the importance of these genes during the initial stages of the domestication process traditionally rests on the assumption that robust inferences about the past can be made on the basis of modern genetic datasets. A growing body of evidence from ancient DNA studies, however, has revealed that ancient and even historic populations often bear little resemblance to their modern counterparts. Here, we test the temporal context of selection on specific genetic loci known to differentiate modern domestic chickens from their extant wild ancestors. We extracted DNA from 80 ancient chickens excavated from 12 European archaeological sites, dated from ∼ 280 B.C. to the 18th century A.D. We targeted three unlinked genetic loci: the mitochondrial control region, a gene associated with yellow skin color (β-carotene dioxygenase 2), and a putative domestication gene thought to be linked to photoperiod and reproduction (thyroid-stimulating hormone receptor, TSHR). Our results reveal significant variability in both nuclear genes, suggesting that the commonality of yellow skin in Western breeds and the near fixation of TSHR in all modern chickens took place only in the past 500 y. In addition, mitochondrial variation has increased as a result of recent admixture with exotic breeds. We conclude by emphasizing the perils of inferring the past from modern genetic data alone.
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