ArticleProceedings of the National Academy of Sciences of the United States of America2014
Genomic and cranial phenotype data support multiple modern human dispersals from Africa and a southern route into Asia.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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53 citing papers in PubMed.
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- Semicircular canals shed light on bottleneck events in the evolution of the Neanderthal clade.Nature communications · 2025Article
- Bioclimatic and masticatory influences on human cranial diversity verified by analysis of 3D morphometric homologous models.Scientific reports · 2024Article
- "Feeling at home in Vanuatu": Integration of newcomers from the East during the last millennium.PloS one · 2024Article
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- Early presence of Homo sapiens in Southeast Asia by 86-68 kyr at Tam Pà Ling, Northern Laos.Nature communications · 2023Article
- Extended longevity of DNA preservation in Levantine Paleolithic sediments, Sefunim Cave, Israel.Scientific reports · 2022Article
- Global patterns of the cranial form of modern human populations described by analysis of a 3D surface homologous model.Scientific reports · 2022Article
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- Contrasting maternal and paternal genetic histories among five ethnic groups from Khyber Pakhtunkhwa, Pakistan.Scientific reports · 2022Article
- Female craniometrics support the 'two-layer model' of human dispersal in Eastern Eurasia.Scientific reports · 2021Article
- The evolution of human skin pigmentation involved the interactions of genetic, environmental, and cultural variables.Pigment cell & melanoma research · 2021Review
- Origins of modern human ancestry.Nature · 2021Review
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- Testing the utility of dental morphological trait combinations for inferring human neutral genetic variation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- The Early Peopling of the Philippines based on mtDNA.Scientific reports · 2020Article
- Al-Ansab and the Dead Sea: Mid-MIS 3 archaeology and environment of the early Ahmarian population of the Levantine corridor.PloS one · 2020Article
- Ancient origins of low lean mass among South Asians and implications for modern type 2 diabetes susceptibility.Scientific reports · 2019Article
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Abstract
Despite broad consensus on Africa as the main place of origin for anatomically modern humans, their dispersal pattern out of the continent continues to be intensely debated. In extant human populations, the observation of decreasing genetic and phenotypic diversity at increasing distances from sub-Saharan Africa has been interpreted as evidence for a single dispersal, accompanied by a series of founder effects. In such a scenario, modern human genetic and phenotypic variation was primarily generated through successive population bottlenecks and drift during a rapid worldwide expansion out of Africa in the Late Pleistocene. However, recent genetic studies, as well as accumulating archaeological and paleoanthropological evidence, challenge this parsimonious model. They suggest instead a "southern route" dispersal into Asia as early as the late Middle Pleistocene, followed by a separate dispersal into northern Eurasia. Here we test these competing out-of-Africa scenarios by modeling hypothetical geographical migration routes and assessing their correlation with neutral population differentiation, as measured by genetic polymorphisms and cranial shape variables of modern human populations from Africa and Asia. We show that both lines of evidence support a multiple-dispersals model in which Australo-Melanesian populations are relatively isolated descendants of an early dispersal, whereas other Asian populations are descended from, or highly admixed with, members of a subsequent migration event.
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