ReviewApplied biochemistry and biotechnology2014
Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses.
Review in Applied biochemistry and biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
98 citing papers in PubMed, 283 citations in OpenAlex.
- Recent advances in chemiluminescence probes for Tumor microenvironment with applications in cancer diagnosis and therapy.Pharmaceutical science advances · 2026Review
- Machine learning-assisted paper-based chemiluminescence biosensor for choline quantification in infant milk: toward portable nutritional quality monitoring.Scientific reports · 2026Article
- Triple composite based on metal-organic framework: differences in production of reactive oxygen species in biological and non-biological media.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- Article
- The Antioxidant Activity of a Prepared Cream Containing Saffron Extract and Grape Seed Extract.BioMed research international · 2026Article
- Sensitive chemiluminescent determination of CYFRA 21-1 as a lung cancer marker using PVP/NiO-supported luminol@ZIF-67-aptamer composite.Mikrochimica acta · 2025Article
- Synthesis, Photophysical, and Chemiexcitation Properties of Luminol-Fullerene Dyads: Toward Chemiexcitation Electron Transfer.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Spatial Mapping of OH Radicals Produced by Electric Discharge in Hydrodynamic Cavitation Cloud.The journal of physical chemistry letters · 2025Article
- A Novel Flow Injection Method with Chemiluminescence Detection for the Determination of Carmoisine in Gelatin Desserts.Journal of fluorescence · 2025Article
- Role of SIRT3 in the regulation of Gadd45α expression and DNA repair in β-cells.The Journal of biological chemistry · 2025Article
- A new sequential dual flow lab-on-a-chip with a lyophilized one-component chemiluminescence substrate for high-sensitive microchannel lateral flow assay (mLFA).Sensors & diagnostics · 2025Article
- Chemiluminescent 2-Coumaranones: Synthesis, Luminescence Mechanism, and Emerging Applications.Molecules (Basel, Switzerland) · 2025Review
- Surface Functionalization of ITO for Dual-Mode Hypoxia-Associated Cancer Biomarker Detection.Biosensors · 2025Article
- Mucin 5AC Promotes Breast Cancer Brain Metastasis through cMET/CD44v6.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025Article
- Tools to study microbial iron homeostasis and oxidative stress: current techniques and methodological gaps.Frontiers in molecular biosciences · 2025Review
- Co-delivery of anti-inflammatory and antioxidant agents via polymersomes for osteoarthritis therapy.Frontiers in pharmacology · 2025Article
- Electrogenerated chemiluminescence from luminol-labelled microbeads triggered by in situ generation of hydrogen peroxide.Analytical and bioanalytical chemistry · 2024Article
- Innovations in Nuclear Medicine Imaging for Reactive Oxygen Species: Applications and Radiopharmaceuticals.Antioxidants (Basel, Switzerland) · 2024Review
- Oxidative Stress-Associated Male Infertility: Current Diagnostic and Therapeutic Approaches.Medicina (Kaunas, Lithuania) · 2024Review
- Vanillin-Isatin Hybrid-Induced MARK4 Inhibition As a Promising Therapeutic Strategy against Hepatocellular Carcinoma.ACS omega · 2024Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
Chemiluminescence (CL) is an important method for quantification and analysis of various macromolecules. A wide range of CL agents such as luminol, hydrogen peroxide, fluorescein, dioxetanes and derivatives of oxalate, and acridinium dyes are used according to their biological specificity and utility. This review describes the application of luminol chemiluminescence (LCL) in forensic, biomedical, and clinical sciences. LCL is a very useful detection method due to its selectivity, simplicity, low cost, and high sensitivity. LCL has a dynamic range of applications, including quantification and detection of macro and micromolecules such as proteins, carbohydrates, DNA, and RNA. Luminol-based methods are used in environmental monitoring as biosensors, in the pharmaceutical industry for cellular localization and as biological tracers, and in reporter gene-based assays and several other immunoassays. Here, we also provide information about different compounds that may enhance or inhibit the LCL along with the effect of pH and concentration on LCL. This review covers most of the significant information related to the applications of luminol in different fields.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.