ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2014
Primary intracranial leiomyosarcoma of the torcular Herophili associated with Fanconi anemia and allogenic stem cell transplantation.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 4 citations in OpenAlex.
- EBV-associated leiomyosarcoma in an immunocompromised child: A unique intracranial case with genomic study.International journal of surgery case reports · 2025Article
- Giant primary intracranial multi-fossa leiomyosarcoma involving the frontal sinus, ethmoid air cells, anterior fossa, middle fossa, and intraventricular space: A case report and literature review.Surgical neurology international · 2023Article
- Surgical management and long-term outcomes of primary intracranial leiomyosarcoma: a case series and review of literature.Neurosurgical review · 2021Article
- Primary Intracranial Leiomyosarcoma Secondary to Glioblastoma: Case Report and Literature Review.Frontiers in oncology · 2021Article
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5 authors at 1 institution in 1 country.
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Abstract
purposeFanconi anemia is associated with a high risk for developing malignant tumors. The occurrence of primary intracranial leiomyosarcoma, however, which in general has a poor prognosis, has not been described thus far. The purpose of this study is to report on management and outcome of leiomyosarcoma of the torcular Herophili associated with Fanconi anemia in a pediatric patient. CASE REPORT: A 12-year-old girl with Fanconi anemia presented with a primary intracranial leiomyosarcoma arising from the torcular Herophili and infiltrating the adjacent venous sinuses after previous allogenic hematopoietic stem cell transplantation. Radical tumor resection followed by radiotherapy resulted in tumor-free survival and good outcome at a 2-year follow-up.
conclusionDespite occurrence of leiomyosarcoma in a site thought unfavorable for surgery, combined tumor resection and radiosurgery may yield excellent outcome.
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