ArticleThe Journal of comparative neurology2014
Cortical innervation of the hypoglossal nucleus in the non-human primate (Macaca mulatta).
Article in The Journal of comparative neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Oral somatosensation shapes lingual muscle maps in macaque orofacial primary motor cortex.bioRxiv : the preprint server for biology · 2026Article
- Orofacial Central Pattern Generators: Neuroanatomical and Clinical Insights into Sensory, Motor, Emotional Integration.Experimental neurobiology · 2026Review
- Research advances in dysphagia animal models.Animal models and experimental medicine · 2025Review
- The Brain of the African Wild Dog. VI. The Motor System.The Journal of comparative neurology · 2025Article
- Cerebellar control of targeted tongue movements.The Journal of physiology · 2025Article
- Biomechanical and Cortical Control of Tongue Movements During Chewing and Swallowing.Dysphagia · 2024Review
- Differential impact of unilateral stroke on the bihemispheric motor cortex representation of the jaw and tongue muscles in young and aged rats.Frontiers in neurology · 2024Article
- The evidence against somatotopic organization of function in the primate corticospinal tract.Brain : a journal of neurology · 2023Review
- Towards a somatosensory theory of speech perception.Journal of neurophysiology · 2022Review
- Central activation deficits contribute to post stroke lingual weakness in a rat model.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Where did language come from? Precursor mechanisms in nonhuman primates.Current opinion in behavioral sciences · 2018Article
- Localization of orofacial representation in the corona radiata, internal capsule and cerebral peduncle in Macaca mulatta.The Journal of comparative neurology · 2017Article
- Cytoarchitecture and cortical connections of the anterior insula and adjacent frontal motor fields in the rhesus monkey.Brain research bulletin · 2015Article
- Vulnerability of the medial frontal corticospinal projection accompanies combined lateral frontal and parietal cortex injury in rhesus monkey.The Journal of comparative neurology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The corticobulbar projection to the hypoglossal nucleus was studied from the frontal, parietal, cingulate, and insular cortices in the rhesus monkey by using high-resolution anterograde tracers and stereology. The hypoglossal nucleus received bilateral input from the face/head region of the primary (M1), ventrolateral pre- (LPMCv), supplementary (M2), rostral cingulate (M3), and caudal cingulate (M4) motor cortices. Additional bilateral corticohypoglossal projections were found from the dorsolateral premotor cortex (LPMCd), ventrolateral proisocortical motor area (ProM), ventrolateral primary somatosensory cortex (S1), rostral insula, and pregenual region of the anterior cingulate gyrus (areas 24/32). Dense terminal projections arose from the ventral region of M1, and moderate projections from LPMCv and rostral part of M2, with considerably fewer hypoglossal projections arising from the other cortical regions. These findings demonstrate that extensive regions of the non-human primate cerebral cortex innervate the hypoglossal nucleus. The widespread and bilateral nature of this corticobulbar connection suggests recovery of tongue movement after cortical injury that compromises a subset of these areas, may occur from spared corticohypoglossal projection areas located on the lateral, as well as medial surfaces of both hemispheres. Since functional imaging studies have shown that homologous cortical areas are activated in humans during tongue movement tasks, these corticobulbar projections may exist in the human brain.
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