ArticleCellular and molecular neurobiology2014
Increased dynamin-1 and -2 protein expression in the aged gerbil hippocampus.
Article in Cellular and molecular neurobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Proteomic Insights into Heroin Use: Links to Neurodegeneration.Molecular neurobiology · 2026Article
- Cellular and Molecular Differences Between Area CA1 and the Dentate Gyrus of the Hippocampus.Molecular neurobiology · 2019Review
- Age-dependent decrease of Nurr1 protein expression in the gerbil hippocampus.Biomedical reports · 2018Article
- Time-Course Change of Redd1 Expressions in the Hippocampal CA1 Region Following Chronic Cerebral Hypoperfusion.Cellular and molecular neurobiology · 2017Article
- Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome.Journal of proteome research · 2016Article
- Age‑dependent increase in the expression of antioxidant‑like protein‑1 in the gerbil hippocampus.Molecular medicine reports · 2016Article
- Age-dependent changes in the protein expression levels of Redd1 and mTOR in the gerbil hippocampus during normal aging.Molecular medicine reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dynamin (DNM) plays roles in membrane dynamics, vesicle formation, and transport. In the present study, we compared DNM-1 and DNM-2 protein expressions between the adult (postnatal month 6) and aged (postnatal month 24) gerbil hippocampus using immunohistochemistry and western blot analysis. DNM-1 and DNM-2 immunoreactivities were primarily observed in hippocampal principal neurons: pyramidal cells in the hippocampus proper (CA1-CA3) and granule cells in the dentate gyrus. DNM-1 and DNM-2 immunoreactivities in principal neurons were significantly increased in the aged group compared with the adult group. In addition, DNM-1 and DNM-2 protein levels as well as phospho-DNM-1 level were significantly increased in the aged group. These results indicate that the increases of DNM-1 and DNM-2 protein expressions may reflect the age-related changes in hippocampal function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.