Evidence map›Paper›PMID 24752259›Full record

ArticleAntimicrobial agents and chemotherapy2014

Complete nucleotide sequence of two multidrug-resistant IncR plasmids from Klebsiella pneumoniae.

Fabrice Compain, Lionel Frangeul, Laurence Drieux, Charlotte Verdet, Sylvain Brisse, Guillaume Arlet, Dominique Decré

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Persistent multispecies dissemination ofJournal of clinical microbiology · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Molecular characterization of theFrontiers in veterinary science · 2024
    Article
  9. Article
  10. First report of coexistence ofFrontiers in microbiology · 2023
    Article
  11. Article
  12. Article
  13. Epidemiology of Plasmids inAntibiotics (Basel, Switzerland) · 2022
    Article
  14. New insights about the EptA protein and its correlation with theCurrent research in microbial sciences · 2021
    Article
  15. Article
  16. Outbreak of multi-drug-resistant (MDR) Shigella flexneri in northern Australia due to an endemic regional clone acquiring an IncFII plasmid.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  17. Article
  18. Article
  19. Deceiving Phenotypic Susceptibility Results on aFrontiers in cellular and infection microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fabrice CompainLaboratoire de Bactériologie, Faculté de Médecine, Université Pierre et Marie Curie, Paris, France.
Lionel FrangeulGénopole, Institut Pasteur, Paris, France.
Laurence DrieuxLaboratoire de Bactériologie, Faculté de Médecine, Université Pierre et Marie Curie, Paris, France Laboratoire de Bactériologie-Hygiène, Hôpitaux Universitaires la Pitié Salpêtrière-Charles Foix, Assistance Publique des Hôpitaux de Paris, Paris, France.
Charlotte VerdetDépartement de Bactériologie, Hôpitaux de l'Est Parisien, Assistance Publique des Hôpitaux de Paris, Paris, France.
Sylvain BrisseMicrobial Evolutionary Genomics, Institut Pasteur, Paris, France CNRS, Paris, France.
Guillaume ArletLaboratoire de Bactériologie, Faculté de Médecine, Université Pierre et Marie Curie, Paris, France Département de Bactériologie, Hôpitaux de l'Est Parisien, Assistance Publique des Hôpitaux de Paris, Paris, France.
Dominique DecréLaboratoire de Bactériologie, Faculté de Médecine, Université Pierre et Marie Curie, Paris, France Département de Bactériologie, Hôpitaux de l'Est Parisien, Assistance Publique des Hôpitaux de Paris, Paris, France dominique.decre@upmc.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here the complete nucleotide sequence of two IncR replicons encoding multidrug resistance determinants, including β-lactam (blaDHA-1, blaSHV-12), aminoglycoside (aphA1, strA, strB), and fluoroquinolone (qnrB4, aac6'-1b-cr) resistance genes. The plasmids have backbones that are similar to each other, including the replication and stability systems, and contain a wide variety of transposable elements carrying known antibiotic resistance genes. This study confirms the increasing clinical importance of IncR replicons as resistance gene carriers.

Indexed as

AminoglycosidesAnti-Bacterial AgentsBase Sequencebeta-Lactamasesbeta-Lactam ResistanceDNA Transposable ElementsDrug Resistance, Multiple, BacterialFluoroquinolonesGenes, MDRKlebsiella pneumoniaeMicrobial Sensitivity TestsMolecular Sequence DataR FactorsSequence Analysis, DNAAminoglycosidesAnti-Bacterial Agentsbeta-LactamasesDNA Transposable ElementsFluoroquinolones

Identifiers

PMID24752259
PMCPMC4068571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.