ArticleAntimicrobial agents and chemotherapy2014
Emergence of clinical Salmonella enterica serovar Typhimurium isolates with concurrent resistance to ciprofloxacin, ceftriaxone, and azithromycin.
Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 108 citations in OpenAlex.
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- Plasmid-mediated azithromycin resistance in non-typhoidal Salmonella recovered from human infections.The Journal of antimicrobial chemotherapy · 2024Article
- Prevalence and Characteristics of Plasmid-Mediated Fosfomycin Resistance GenePathogens (Basel, Switzerland) · 2024Article
- Prevalence of Multiple Antibiotic Resistance AmongOman medical journal · 2024Article
- Colistin-, cefepime-, and levofloxacin-resistant Salmonella enterica serovars isolated from Egyptian chicken carcasses.Annals of clinical microbiology and antimicrobials · 2024Article
- Emergence and genomic characteristics of multi-drug-resistantMicrobial genomics · 2024Article
- Prevalence and molecular characterization of cefotaxime-resistantMicrobiology spectrum · 2023Article
- Antimicrobial Resistance, Virulence Properties and Genetic Diversity ofPathogens (Basel, Switzerland) · 2023Article
- Emergence of a Hybrid IncI1-Iα Plasmid-EncodedMicroorganisms · 2023Article
- Prevention and Control of HumanInternational journal of food science · 2023Review
- Relationship of OqxAB efflux pump to antibiotic resistance, mainly fluoroquinolones inIranian journal of basic medical sciences · 2023Article
- Phylogenomic Analysis of Salmonella enterica Serovar Indiana ST17, an Emerging Multidrug-Resistant Clone in China.Microbiology spectrum · 2022Article
- Article
- Evolution of ß-lactams, fluroquinolones and colistin resistance and genetic profiles inItalian journal of food safety · 2022Article
- First report of multidrug-resistantVeterinary world · 2022Article
- Draft Whole-Genome Sequences of Two Multidrug-Resistant Salmonella enterica Serovar Senftenberg Sequence Type 14 Strains Resistant to Ciprofloxacin, Ceftriaxone, and/or Azithromycin, Isolated from Kolkata, India.Microbiology resource announcements · 2022Article
- Antimicrobial resistance ofFrontiers in microbiology · 2022Article
- Comparison of Single vs Combination Drug Therapy in Extensively Drug ResistantInfection and drug resistance · 2022Article
- Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases ofAntibiotics (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salmonella infection is an important public health issue for which the needs of antimicrobial treatment are increasing. A total of 546 human clinical S. enterica serovar Typhimurium isolates were recovered from patients in hospitals in China during the period of 2005 to ∼ 2011. Twenty percent of the isolates exhibited resistance to ciprofloxacin, and 4% were resistant to ceftriaxone. Importantly, for the first time, 12 (2%) S. Typhimurium isolates resistant to both ciprofloxacin and ceftriaxone were recovered; among these 12 isolates, two were also resistant to azithromycin, and one was resistant to all other drugs tested. The combined effects of various transferrable extended-spectrum β-lactamase determinants and a novel efflux-based ciprofloxacin resistance mechanism encoded by the mobile efflux gene oqxAB were responsible for the emergence of these extremely (highly) drug-resistant (XDR) S. Typhimurium isolates. The dissemination of resistance genes, such as those encoding ESBLs and the OqxAB pump, among Salmonella organisms will speed up the selection of XDR Salmonella, posing a huge threat to public health and Salmonella infection control.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.