Trial reportEuropean journal of applied physiology2014
Changes in corticospinal excitability during an acute bout of resistance exercise in the elbow flexors.
Trial report in European journal of applied physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Anodal tDCS improves neuromuscular adaptations to short-term resistance training of the knee extensors in healthy individuals.Journal of neurophysiology · 2024Trial
- Effects of acute resistance training modality on corticospinal excitability, intra-cortical and neuromuscular responses.European journal of applied physiology · 2017Trial
- Cross-education of muscular strength is facilitated by homeostatic plasticity.European journal of applied physiology · 2017Trial
- Corticospinal, reticulospinal and motoneuronal contributions to fatigability during a sustained contraction of the elbow flexors.Experimental physiology · 2026Article
- Localized electrocortical activity as a function of single-leg squat phases and its relationship to knee frontal plane stability.Experimental brain research · 2024Article
- Contraction intensity modulates spinal excitability during transcranial magnetic stimulation-evoked silent period in rectus femoris muscle.European journal of applied physiology · 2024Article
- Altitude-induced effects on neuromuscular, metabolic and perceptual responses before, during and after a high-intensity resistance training session.European journal of applied physiology · 2023Article
- Acute neuromuscular and hormonal responses to 20 versus 40% velocity loss in males and females before and after 8 weeks of velocity-loss resistance training.Experimental physiology · 2022Article
- Is there Evidence for the Suggestion that Fatigue Accumulates Following Resistance Exercise?Sports medicine (Auckland, N.Z.) · 2022Review
- The Time-Course of Acute Changes in Corticospinal Excitability, Intra-Cortical Inhibition and Facilitation Following a Single-Session Heavy Strength Training of the Biceps Brachii.Frontiers in human neuroscience · 2016Article
- Different corticospinal control between discrete and rhythmic movement of the ankle.Frontiers in human neuroscience · 2014Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHypertrophic resistance exercise (HRE) induces central and peripheral fatigue. However, more detailed information about changes in corticospinal excitability remains to be elucidated.
methodsEleven volunteers participated in the upper arm HRE which included one repetition maximum (1 RM) control contractions and three sets of 13 RM (SET1-3). Transcranial magnetic stimulation (TMS) was applied during maximal isometric voluntary contraction (MVC) at the end of each set and during control contractions to study changes in corticospinal excitability. Electrical stimulation was used in order to measure peripheral changes.
resultsMVC decreased after each set when compared to control contractions. Motor evoked potential (MEP) were 138.7 ± 52.7 % (p < 0.05), 130.4 ± 44.7 and 113.1 ± 31.4 % after SET1, SET2 and SET3, respectively, when compared to pre-exercise value. A significant reduction in MEP area between SET1 and SET3 (p < 0.05) was observed while silent period (SP) duration increased (~151-165 ms, p < 0.05) simultaneously between these sets. TMS-evoked twitch force during MVC increased significantly following each set when compared to pre-exercise value. Simultaneously, a significant reduction was observed in resting twitch force over the sets.
conclusionsThe results of this study clearly support the existence of both central and peripheral fatigue during HRE of elbow flexors. However, changes in the MEP area and SP suggest that during HRE of the elbow flexors, the corticospinal excitability increases first, until at some point, supraspinal fatigue takes over.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.