ArticleRetina (Philadelphia, Pa.)2014
Outer retinal structure after closed-globe blunt ocular trauma.
Article in Retina (Philadelphia, Pa.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 44 citations in OpenAlex.
- REPEATABILITY AND LONGITUDINAL ASSESSMENT OF FOVEAL CONE STRUCTURE IN CNGB3-ASSOCIATED ACHROMATOPSIA.Retina (Philadelphia, Pa.) · 2017Trial
- A porcine commotio retinae model for preclinical evaluation of posttraumatic photoreceptor degeneration.JCI insight · 2026Article
- Exploring computerized tomography findings and ocular trauma score in open globe injuries: assessing imaging's predictive value.BMC ophthalmology · 2025Article
- The USH3A causative gene clarin1 functions in Müller glia to maintain retinal photoreceptors.PLoS genetics · 2025Article
- The USH3A causative gene clarin1 functions in Müller glia to maintain retinal photoreceptors.bioRxiv : the preprint server for biology · 2024Article
- Comparison of Cone Mosaic Metrics From Images Acquired With the SPECTRALIS High Magnification Module and Adaptive Optics Scanning Light Ophthalmoscopy.Translational vision science & technology · 2022Article
- Challenges Associated With Ellipsoid Zone Intensity Measurements Using Optical Coherence Tomography.Translational vision science & technology · 2021Article
- Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel.Translational vision science & technology · 2021Article
- Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO).Progress in retinal and eye research · 2021Review
- A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head.Scientific reports · 2019Article
- Cellular-scale evaluation of induced photoreceptor degeneration in the living primate eye.Biomedical optics express · 2019Article
- Assessment of Outer Retinal Remodeling in the Hibernating 13-Lined Ground Squirrel.Investigative ophthalmology & visual science · 2018Article
- Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa.Translational vision science & technology · 2018Article
- Assessing photoreceptor structure in patients with traumatic head injury.BMJ open ophthalmology · 2018Article
- Quantitative analysis of photoreceptor layer reflectivity on en-face optical coherence tomography as an estimator of cone density.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017Article
- Photoreceptor-Based Biomarkers in AOSLO Retinal Imaging.Investigative ophthalmology & visual science · 2017Review
- The Effect of Retinal Melanin on Optical Coherence Tomography Images.Translational vision science & technology · 2017Article
- High-Resolution Imaging of Intraretinal Structures in Active and Resolved Central Serous Chorioretinopathy.Investigative ophthalmology & visual science · 2017Article
- Detection of airbag impact-induced cone photoreceptor damage by adaptive optics scanning laser ophthalmoscopy: a case report.BMC ophthalmology · 2016Article
- Evaluating Descriptive Metrics of the Human Cone Mosaic.Investigative ophthalmology & visual science · 2016Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 1 country.
Funding
Abstract
purposeTo evaluate outer retinal structural abnormalities in patients with visual deficits after closed-globe blunt ocular trauma.
methodsNine subjects with visual complaints after closed-globe blunt ocular trauma were examined between 1 month after trauma and 6 years after trauma. Spectral domain optical coherence tomography was used to assess the outer retinal architecture, whereas adaptive optics scanning light ophthalmoscopy was used to analyze the photoreceptor mosaic integrity.
resultsVisual deficits ranged from central scotomas to decreased visual acuity. Spectral domain optical coherence tomography defects included focal foveal photoreceptor lesions, variable attenuation of the interdigitation zone, and mottling of the outer segment band, with one subject having normal outer retinal structure. Adaptive optics scanning light ophthalmoscopy revealed disruption of the photoreceptor mosaic in all subjects, variably manifesting as foveal focal discontinuities, perifoveal hyporeflective cones, and paracentral regions of selective cone loss.
conclusionWe observe persistent outer retinal disruption in subjects with visual complaints after closed-globe blunt ocular trauma, albeit to a variable degree. Adaptive optics scanning light ophthalmoscopy imaging allows the assessment of photoreceptor structure at a level of detail not resolvable using spectral domain optical coherence tomography or other current clinical imaging tools. Multimodal imaging seems to be useful in revealing the cause of visual complaints in patients after closed-globe blunt ocular trauma. Future studies are needed to better understand how photoreceptor structure changes longitudinally in response to various traumas.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.