Evidence map›Paper›PMID 24751935›Full record

ArticleScientific reports2014

Functional near infrared spectroscopy (fNIRS) to assess cognitive function in infants in rural Africa.

Sarah Lloyd-Fox, M Papademetriou, M K Darboe, N L Everdell, R Wegmuller, A M Prentice, S E Moore, C E Elwell

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05629624 (Multidimensional Evaluation of the Early Emergence of Executive Function and Emotional Regulation in Young Children in Bangladesh Using Nutritional and Psychosocial Intervention), which is not on this map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05629624 nacompletednot on this mapstarted 2022, after this paper: background citation

Multidimensional Evaluation of the Early Emergence of Executive Function and Emotional Regulation in Young Children in Bangladesh Using Nutritional and Psychosocial Intervention: A Pilot Study

TypeinterventionalSponsorBoston Children's HospitalRan2022 to 2025Enrolled297ConditionsExecutive Function Disorder, Emotional Regulation, Malnutrition, ChildArmsChickpea based RUSF, E-RUSF, Outcome reference group/RUSF
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sarah Lloyd-FoxCentre for Brain and Cognitive Development, Birkbeck, University of London.
M PapademetriouDepartment of Medical Physics and Bioengineering, University College London.
M K DarboeMedical Research Council (MRC) International Nutrition Group, MRC Keneba, MRC Unit, The Gambia.
N L EverdellDepartment of Medical Physics and Bioengineering, University College London.
R WegmullerMedical Research Council (MRC) International Nutrition Group, MRC Keneba, MRC Unit, The Gambia.
A M Prentice1] Medical Research Council (MRC) International Nutrition Group, MRC Keneba, MRC Unit, The Gambia [2] MRC International Nutrition Group, London School of Hygiene & Tropical Medicine, London, UK.
S E Moore1] Medical Research Council (MRC) International Nutrition Group, MRC Keneba, MRC Unit, The Gambia [2] MRC International Nutrition Group, London School of Hygiene & Tropical Medicine, London, UK.
C E ElwellDepartment of Medical Physics and Bioengineering, University College London.
MRC Unit the Gambia · GMUniversity College London · GBBirkbeck, University of London · GB

Funding

Medical Research Council G0701484Medical Research Council MC_U123292701Medical Research Council MR/K021389/1
6 · The paper itself

Abstract

Cortical mapping of cognitive function during infancy is poorly understood in low-income countries due to the lack of transportable neuroimaging methods. We have successfully piloted functional near infrared spectroscopy (fNIRS) as a neuroimaging tool in rural Gambia. Four-to-eight month old infants watched videos of Gambian adults perform social movements, while haemodynamic responses were recorded using fNIRS. We found distinct regions of the posterior superior temporal and inferior frontal cortex that evidenced either visual-social activation or vocally selective activation (vocal > non-vocal). The patterns of selective cortical activation in Gambian infants replicated those observed within similar aged infants in the UK. These are the first reported data on the measurement of localized functional brain activity in young infants in Africa and demonstrate the potential that fNIRS offers for field-based neuroimaging research of cognitive function in resource-poor rural communities.

Indexed as

Public Health SurveillanceSpectroscopy, Near-InfraredAfricaCerebral CortexCognitionFemaleHemodynamicsHumansInfantMaleNeuroimagingOxyhemoglobinsRural HealthOxyhemoglobins

Identifiers

PMID24751935
PMCPMC5381189
OpenAlexW2028899648

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.