Evidence map›Paper›PMID 24751824›Full record

ReviewMethods (San Diego, Calif.)2014

Studying aging in Drosophila.

Ying He, Heinrich Jasper

Abstract readReview
In one paragraph

Review in Methods (San Diego, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Distribution Analysis of the Lifespan Trait in Drosophila.International journal of molecular sciences · 2025
    Article
  5. Age-related degradation of behavioral and network features ofbioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. eNeuro · 2025
    Article
  8. Article
  9. Studying Cellular Senescence Using the Model Organism Drosophila melanogaster.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Experimental models for ageing research.Histology and histopathology · 2023
    Review
  19. Review
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ying HeBuck Institute for Research on Aging, Novato, CA, USA.
Heinrich JasperBuck Institute for Research on Aging, Novato, CA, USA. Electronic address: HJasper@buckinstitute.org.

Funding

Regulation of UV-Induced ApoptosisR01EY018177 · NEI · UNIVERSITY OF ROCHESTER · PI JASPER, HEINRICH · 2008 to 2018
$3.1M
Systemic coordination of stress responses by insulin signalingR01AG028127 · NIA · UNIVERSITY OF ROCHESTER · PI JASPER, HEINRICH · 2006 to 2015
$3.0M
Redox Signaling and Stem Cell FunctionR01GM100196 · NIGMS · UNIVERSITY OF ROCHESTER · PI BOHMANN, DIRK, JASPER, HEINRICH · 2012 to 2015
$1.7M
NEI NIH HHS R01 EY018177NIA NIH HHS R01 AG028127NIGMS NIH HHS R01 GM100196
6 · The paper itself

Abstract

Drosophila melanogaster represents one of the most important genetically accessible model organisms for aging research. Studies in flies have identified single gene mutations that influence lifespan and have characterized endocrine signaling interactions that control homeostasis systemically. Recent studies have focused on the effects of aging on specific tissues and physiological processes, providing a comprehensive picture of age-related tissue dysfunction and the loss of systemic homeostasis. Here we review methodological aspects of this work and highlight technical considerations when using Drosophila to study aging and age-related diseases.

Indexed as

AgingAnimalsDevelopmental BiologyDrosophilaHomeostasisModels, AnimalAgingDegenerationDrosophilaHomeostasis

Identifiers

PMID24751824
PMCPMC4066732

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.