ArticleObesity reviews : an official journal of the International Association for the Study of Obesity2014
Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons - a scoping review.
Article in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 176 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
176 citing papers in PubMed, 4 syntheses or guidelines pooled it, 363 citations in OpenAlex.
- Prognostic Factors and Changes in Pain, Physical Functioning, and Participation in Patients With Hip and/or Knee Osteoarthritis: A Systematic Review.Arthritis care & research · 2025Pooled it
- Outcomes of Partial Meniscectomy in Obese Patients: A Systematic Review and Meta-Analysis.Cartilage · 2021Pooled it
- Prevalence and incidence of osteoarthritis among people living in the Gulf Cooperation Council countries: a systematic review and meta-analysis.Clinical rheumatology · 2021Pooled it
- Extracorporeal shockwave therapy for the treatment of knee osteoarthritis: a meta-analysis.International orthopaedics · 2020Pooled it
- Effect of weight loss and liraglutide on neutrophil gelatinase-associated lipocalin levels among individuals with overweight and knee osteoarthritis: Exploratory analyses of a randomized controlled trial.Osteoarthritis and cartilage open · 2025Trial
- How Does Exercise, With and Without Diet, Improve Pain and Function in Knee Osteoarthritis? A Secondary Analysis of a Randomized Controlled Trial Exploring Potential Mediators of Effects.Arthritis care & research · 2023Trial
- Trial
- The effect of a web-based psychoeducation on emotional functioning, eating behaviors, and body image among premenopausal women with excess body weight.Archives of women's mental health · 2021Trial
- Efficacy of Triamcinolone Acetonide Extended-Release in Participants with Unilateral Knee Osteoarthritis: A Post Hoc Analysis.Advances in therapy · 2019Trial
- Effectiveness of Cucumis sativus extract versus glucosamine-chondroitin in the management of moderate osteoarthritis: a randomized controlled trial.Clinical interventions in aging · 2018Trial
- Phenotypic Factors and Celecoxib Efficacy in Knee OA: A Post‑hoc Pooled Analysis of Two Randomized, Double‑Blind, Placebo‑Controlled Trials.Pain and therapy · 2026Article
- Chronic Pain in Older Adults: Risk Factors and Prevention.Life (Basel, Switzerland) · 2026Review
- Epidemiology of osteoarthritis overall and by body mass index category in the United States: A retrospective analysis of the National Health and Nutrition Examination Survey.Obesity pillars · 2026Article
- Clinical and Economic Burden Among People with Knee Osteoarthritis and Obesity in the United States: A Retrospective Analysis.Rheumatology and therapy · 2026Article
- Unconventional Applications of Semaglutide and Tirzepatide: From Oncology to Human Reproduction.Biomedicines · 2026Review
- Advanced glycation end product accumulation and AGEs-RAGE axis biomarkers in plasma and synovial fluid are associated with osteoarthritis severity.Biomolecules & biomedicine · 2026Observational
- Letter to the Editor: Early intervention in knee osteoarthritis with genicular artery embolization is associated with improved clinical outcomes.European radiology · 2026Article
- Is lower extremity joint replacement surgery associated with weight loss? An institutional retrospective study of 36,993 cases.International journal of obesity (2005) · 2026Article
- Article
- Osteoarthritis in Saudi Arabia: Unveiling misconceptions and societal determinants of disease interpretation.Journal of family medicine and primary care · 2026Article
116 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is widely acknowledged as a risk factor for both the incidence and progression of osteoarthritis, and has a negative influence on outcomes. Loss of at least 10% of body weight, coupled with exercise, is recognized as a cornerstone in the management of obese patients with osteoarthritis, and can lead to significant improvement in symptoms, pain relief, physical function and health-related quality of life. However, questions still remain surrounding optimal management. Given the significant health, social and economic burden of osteoarthritis, especially in obese patients, it is imperative to advance our knowledge of osteoarthritis and obesity, and apply this to improving care and outcomes. This paper overviews what is already known about osteoarthritis and obesity, discusses current key challenges and ongoing hypotheses arising from research in these areas, and finally, postulates what the future may hold in terms of new horizons for obese patients with osteoarthritis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.