ArticleThe Journal of surgical research2014
Identifying predictors of a difficult thyroidectomy.
Article in The Journal of surgical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Management of perioperative thyrotoxicosis - what to do when standard therapy is contraindicated or fails?Frontiers in endocrinology · 2024Pooled it
- The significance of Hashimoto's thyroiditis for postoperative complications of thyroid surgery: a systematic review and meta-analysis.Annals of the Royal College of Surgeons of England · 2021Pooled it
- Article
- Effect of Intraoperative Nerve Monitorization on Predicting Vocal Cord Paralysis in Thyroid Surgery.International archives of otorhinolaryngology · 2026Article
- Serum-negative chronic thyroiditis: an insidious nosographic entity cause of hypothyroidism, goiter and difficult thyroidectomy.Endocrine · 2025Article
- Exploring Post-Thyroidectomy Hypocalcemia in the Background of Thyroiditis- A Comparative Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Nomogram for predicting difficult transoral and submental thyroidectomy: a retrospective model development and validation study with large-scale population.Surgical endoscopy · 2025Article
- Evaluation of Preoperative Factors as Predictors of Difficult Thyroidectomy: A Prospective Study.Cureus · 2025Article
- Analysis of preoperative influential factors and construction of a predictive nomogram of difficult thyroidectomy.BMC surgery · 2023Article
- Risk factors for difficult thyroidectomy and postoperative morbidity do not match: retrospective study from an endocrine surgery academic referral centre.Updates in surgery · 2022Article
- Preoperative Serum Macrophage Migration Inhibitory Factor Level Correlates with Surgical Difficulty and Outcome in Patients with Autoimmune Thyroiditis.Journal of clinical medicine · 2021Article
- Energy vessel sealant devices are associated with decreased risk of neck hematoma after thyroid surgery.Updates in surgery · 2020Article
- Assessing American Thyroid Association Guidelines for Total Thyroidectomy in Graves' Disease.The Journal of surgical research · 2020Article
- Patient, thyroid, and surgeon related factors that make thyroidectomy difficult-cohort study.Annals of medicine and surgery (2012) · 2020Article
- An evaluation score of the difficulty of thyroidectomy considering operating time and preservation of recurrent laryngeal nerve.Updates in surgery · 2019Article
- Thyroiditis process as a predictive factor of sternotomy in the treatment of cervico-mediastinal goiter.BMC surgery · 2019Article
- May predictors of difficulty in thyroid surgery increase the incidence of complications? Prospective study with the proposal of a preoperative score.BMC surgery · 2019Article
- Impact of potassium iodide on thyroidectomy for Graves' disease: Implications for safety and operative difficulty.Surgery · 2018Article
- Determinants of operative time in thyroid surgery: A prospective multicenter study of 3454 thyroidectomies.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundA Thyroidectomy Difficulty Scale (TDS) was previously developed that identified more difficult operations, which correlated with longer operative times and higher complication rates. The purpose of this study was to identify preoperative variables predictive of a more difficult thyroidectomy using the TDS.
methodsA four item, 20-point TDS, was used to score the difficulty of thyroid operations. Patient and disease factors were recorded for each patient. Difficult thyroidectomy and non-difficult thyroidectomy (NDT) patients were compared. A final multivariate logistic regression model was constructed with significant (P<0.05) variables from a univariate analysis.
resultsA total of 189 patients were scored using TDS. Of them, 69 (36.5%) suffered from hyperthyroidism, 42 (22.2%) from Hashimotos, 34 (18.0%) from thyroid cancer, and 36 (19.0%) from multinodular goiter. Among hyperthyroid patients, the DT group had a greater number preoperatively treated with Lugols potassium iodide (81.6% DT versus 58.1% NDT, P=0.032), presence of ophthalmopathy (31.6% DT versus 9.7% NDT, P=0.028), and presence of (>4 IU/mL) antithyroglobulin antibodies (34.2% DT versus 12.9% NDT, P=0.05). Using multivariate analysis, hyperthyroidism (odds ratio [OR], 4.35, 95% confidence interval [CI], 1.23-15.36, P=0.02), presence of antithyroglobulin antibody (OR, 3.51, 95% CI, 1.28-9.66, P=0.015), and high (>150 ng/mL) thyroglobulin (OR, 2.61, 95% CI, 1.06-6.42, P=0.037) were independently associated with DT.
conclusionsUsing TDS, we demonstrated that a diagnosis of hyperthyroidism, preoperative elevation of serum thyroglobulin, and antithyroglobulin antibodies are associated with DT. This tool can assist surgeons in counseling patients regarding personalized operative risk and improve OR scheduling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.