ArticleEmerging infectious diseases2014
Bovine leukemia virus DNA in human breast tissue.
Article in Emerging infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 130 citations in OpenAlex.
- Integrated expression profiling reveals molecular crosstalk between CFTR, FASN, FRAP (mTOR), and BANK1 in hepatocellular carcinoma.Scientific reports · 2026Article
- Shaping the Future Plate: Exploring the Safety Concerns of Cultivated and Conventional Meat Production.Physiological research · 2026Review
- Article
- Visual typing detection of bovine leukemia virus with a lateral flow immunoassay based on latex microspheres.Archives of virology · 2026Article
- Absence of detectable bovine leukemia virus miRNAs in human cancer small RNA-seq datasets.Microbiology spectrum · 2026Article
- Interferon dynamics in deltaretroviruses: why HTLV-1 evades, but BLV responds.Molecular biology reports · 2026Review
- Article
- Association of the BoLA-DRB3*12:01 allele with resistance to bovine leukosis virus infection in Crioula Lageana cattle.Journal of applied genetics · 2026Article
- Establishment and Characterization of Human Cell Lines Stably Infected With Bovine Leukemia Virus In Vitro Reveals Apoptosis After Latency and Silencing.Transboundary and emerging diseases · 2026Article
- Tissue distribution and quantification of bovine leukemia virus proviral DNA in cows after a long-term infection with wild-type strains and the attenuated BLV vaccine strain.Frontiers in immunology · 2026Article
- Can Oncogenic Animal Viruses Pose a Threat to Humans?Pathogens (Basel, Switzerland) · 2025Review
- Virological perspectives of the current situation of oncogenic viruses in Egypt: a review.Infectious agents and cancer · 2025Review
- Relationship between bovine leukemia virus (BLV) infection and shedding provirus from milk in cows.Tropical animal health and production · 2025Article
- Bovine Leukemia Virus: Origin, Prevalence, Phylogenetic Diversity, Risk Factors, and Strategies for Control.Animals : an open access journal from MDPI · 2025Review
- Bovine leukemia virus: an emerging concern for zoonotic cross-species transmission.Frontiers in cellular and infection microbiology · 2025Review
- The viral origins of breast cancer.Infectious agents and cancer · 2024Review
- The Role of Oncogenic Viruses in the Pathogenesis of Sporadic Breast Cancer: A Comprehensive Review of the Current Literature.Pathogens (Basel, Switzerland) · 2024Review
- The Global Epidemiology of Bovine Leukemia Virus: Current Trends and Future Implications.Animals : an open access journal from MDPI · 2024Review
- Design and implementation of a TaqManVeterinary research forum : an international quarterly journal · 2024Article
- Exploring the presence of bovine leukemia virus among breast cancer tumors in a rural state.Breast cancer research and treatment · 2023Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. A previous finding of antibodies against BLV in humans led us to examine the possibility of human infection with BLV. We focused on breast tissue because, in cattle, BLV DNA and protein have been found to be more abundant in mammary epithelium than in lymphocytes. In human breast tissue specimens, we identified BLV DNA by using nested liquid-phase PCR and DNA sequencing. Variations from the bovine reference sequence were infrequent and limited to base substitutions. In situ PCR and immunohistochemical testing localized BLV to the secretory epithelium of the breast. Our finding of BLV in human tissues indicates a risk for the acquisition and proliferation of this virus in humans. Further research is needed to determine whether BLV may play a direct role in human disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.